{"id":"W3126274126","doi":"10.1038/s41391-020-00310-3","title":"Treatment of nonmetastatic castration-resistant prostate cancer: focus on second-generation androgen receptor inhibitors","year":2021,"lang":"en","type":"review","venue":"Prostate Cancer and Prostatic Diseases","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Bayer HealthCare","keywords":"Medicine; Enzalutamide; Prostate cancer; Oncology; Androgen deprivation therapy; Internal medicine; Androgen receptor; Disease; Adverse effect; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001386231,0.001116992,0.003117642,0.0004463544,0.000284227,0.000192487,0.0001210713,0.000218467,0.0007092637],"category_scores_gemma":[0.0000639373,0.0007782895,0.0006589684,0.0007547476,0.0003694115,0.0002150876,0.00006401558,0.0002762368,0.00001665242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001068275,"about_ca_system_score_gemma":0.004484111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000351696,"about_ca_topic_score_gemma":0.0001891361,"domain_scores_codex":[0.9953381,0.0003072721,0.001413332,0.001315454,0.0008128465,0.000813033],"domain_scores_gemma":[0.9971481,0.0002775381,0.0007926672,0.000625202,0.000457921,0.0006985875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001072248,0.001101334,0.0008289259,0.03146747,0.002096904,0.0002782819,0.001398826,0.000006389479,0.0002038155,0.00006006069,0.001943931,0.9595418],"study_design_scores_gemma":[0.009887307,0.007479399,0.000203145,0.03401095,0.01094229,0.00008114379,0.0006079387,0.00004840135,0.00422935,0.0001218939,0.9307489,0.001639319],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00805625,0.9654103,6.630336e-7,0.0004895817,0.0004577553,0.007101536,0.01829071,0.00006623216,0.0001270025],"genre_scores_gemma":[0.002189914,0.9790128,0.0001316048,0.00004888826,0.0004139442,0.007429985,0.005646913,0.0001821872,0.004943775],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9579025,"threshold_uncertainty_score":0.9994668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05918462441973871,"score_gpt":0.3692282572156028,"score_spread":0.3100436327958641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}