{"id":"W3126274126","doi":"10.1038/s41391-020-00310-3","title":"Treatment of nonmetastatic castration-resistant prostate cancer: focus on second-generation androgen receptor inhibitors","year":2021,"lang":"en","type":"review","venue":"Prostate Cancer and Prostatic Diseases","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Bayer HealthCare","keywords":"Medicine; Enzalutamide; Prostate cancer; Oncology; Androgen deprivation therapy; Internal medicine; Androgen receptor; Disease; Adverse effect; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001209064,0.0003696509,0.0008445969,0.0006506646,0.0001638352,0.0007843818,0.000644001,0.0006765472,0.001614928],"category_scores_gemma":[0.001414806,0.0001270475,0.0007920986,0.0005860284,0.0003695454,0.0009102426,0.0004452195,0.001781252,0.0003621172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000530182,"about_ca_system_score_gemma":0.00100778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007154036,"about_ca_topic_score_gemma":0.002496149,"domain_scores_codex":[0.9995549,0.0001426892,0.00007522073,0.00007375303,0.0001150459,0.00003826913],"domain_scores_gemma":[0.998686,0.000825742,0.000194761,0.00002120169,0.0002167989,0.00005550557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001809131,0.00007884674,0.0006241382,0.02433229,0.0002598353,0.0003642253,0.0001440327,0.0007855856,0.001567309,0.005286744,0.02998339,0.9363927],"study_design_scores_gemma":[0.0001296976,0.0005453108,0.004076951,0.0218793,0.000631344,0.004060097,0.0002269884,0.0005449464,0.001054411,0.004318368,0.9624906,0.00004195448],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005142293,0.9963736,0.00016891,0.00164964,0.0002378635,0.000004911989,0.00001206322,0.000004681589,0.001034155],"genre_scores_gemma":[0.005245504,0.9919247,0.0003648639,0.001493795,0.0005230538,0.00001085999,0.00002987739,0.000003462853,0.0004038835],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001614928,"threshold_uncertainty_score":0.006394207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05918462441973871,"score_gpt":0.3692282572156028,"score_spread":0.3100436327958641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}