{"id":"W3126559497","doi":"10.3390/ijms22041604","title":"The Ribosome-Binding Mode of Trichothecene Mycotoxins Rationalizes Their Structure—Activity Relationships","year":2021,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Mycotoxins in Agriculture and Food","field":"Agricultural and Biological Sciences","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Agriculture and Agri-Food Canada","funders":"","keywords":"Trichothecene; Mycotoxin; Fusarium; Biology; Binding site; Genetics; Biochemistry; Chemistry; Stereochemistry; Computational biology; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000113303,0.0004415131,0.0003015481,0.00009538608,0.0001522264,0.0002827861,0.0002336927,0.0003066001,0.0009299806],"category_scores_gemma":[0.0002111132,0.000157581,0.000423604,0.0001289167,0.0001282216,0.0002446864,0.0001593554,0.0003663679,0.0004059008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004601883,"about_ca_system_score_gemma":0.0002418401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00222711,"about_ca_topic_score_gemma":0.003381523,"domain_scores_codex":[0.999923,0.00001264064,0.000005035958,0.00002055907,0.00001934874,0.00001943978],"domain_scores_gemma":[0.9999408,0.00001251656,0.00001264488,0.00000830883,0.00001684361,0.000008969203],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000278513,0.0000517844,0.003442934,0.0001578062,0.00003101124,0.0002532997,0.00005817492,0.002924803,0.9873303,0.0008501976,0.0002338037,0.00438749],"study_design_scores_gemma":[0.00003663752,0.0004987716,0.02580907,0.00004291636,0.0001237565,0.0004595068,0.0002831637,0.03271165,0.9253781,0.0008623303,0.01375497,0.00003920248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906074,0.002575384,0.004278784,0.0001937923,0.00002861513,0.00001820434,0.0002185306,0.00009105306,0.001988232],"genre_scores_gemma":[0.9944245,0.001335656,0.002795433,0.00003856704,0.000005107473,0.000008126737,0.0004874259,0.0000139742,0.0008911871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00222711,"threshold_uncertainty_score":0.004428327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02603061662426621,"score_gpt":0.2632087475603529,"score_spread":0.2371781309360867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}