{"id":"W3126698778","doi":"10.1101/2021.02.04.429512","title":"Transcriptomic profiling of canine atrial fibrillation models after one week of sustained arrhythmia","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Atrial fibrillation; Transcriptome; Biology; microRNA; Bioinformatics; Cardiac arrhythmia; Gene; Internal medicine; Gene expression; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002310389,0.0003164807,0.0004869202,0.0001328028,0.00003270579,0.00003772621,0.0001723533,0.0004630335,0.00003130106],"category_scores_gemma":[0.0001115127,0.0003713183,0.0003719583,0.0001904839,0.00009430118,0.00001365112,0.0001689605,0.0001506309,7.925587e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005641642,"about_ca_system_score_gemma":0.00107113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003750429,"about_ca_topic_score_gemma":0.000004900366,"domain_scores_codex":[0.998091,0.0001155886,0.0006308776,0.0006214093,0.0002809183,0.0002601658],"domain_scores_gemma":[0.997816,0.00001040893,0.0004310632,0.0008119507,0.0007727701,0.0001578169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006026921,0.00003967898,0.002941073,0.00066043,0.0002264385,0.000008506092,0.000008894548,0.01374403,0.981616,0.0001389775,0.000009914232,0.000003401469],"study_design_scores_gemma":[0.001319977,0.0001044478,0.01666353,0.0002529874,0.0002395806,2.156353e-8,0.00001094756,0.006549921,0.9742681,0.000004691323,0.0001048285,0.0004809644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862809,0.003799794,0.008623382,0.00006800365,0.000323933,0.0005477301,0.0003203228,0.00002922828,0.000006745386],"genre_scores_gemma":[0.9934761,0.0002717083,0.005322016,0.00002350453,0.0007928534,0.00002631917,0.00001069125,0.00006881399,0.000007992094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01372246,"threshold_uncertainty_score":0.9998739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01259080532323095,"score_gpt":0.2152814334253571,"score_spread":0.2026906281021261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}