{"id":"W3126790097","doi":"10.1007/s10571-021-01048-9","title":"Obligatory Activation of SRC and JNK by GDNF for Survival and Axonal Outgrowth of Postnatal Intestinal Neurons","year":2021,"lang":"en","type":"article","venue":"Cellular and Molecular Neurobiology","topic":"Congenital gastrointestinal and neural anomalies","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Kingston General Hospital; Queen's University","funders":"","keywords":"Glial cell line-derived neurotrophic factor; Axon; Proto-oncogene tyrosine-protein kinase Src; Cell biology; Biology; Enteric nervous system; Neuroscience; Neurotrophin; GDNF family of ligands; Regeneration (biology); Signal transduction; Neuron; Neurotrophic factors; Receptor; Nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002720464,0.0002592146,0.0002221991,0.0003444247,0.0003251223,0.0003083739,0.0002953204,0.0002508642,0.001350439],"category_scores_gemma":[0.0003819185,0.000172273,0.0003250036,0.0001803311,0.0002599095,0.0003480455,0.0004858079,0.0006061514,0.0002401576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005816513,"about_ca_system_score_gemma":0.0006938259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002047877,"about_ca_topic_score_gemma":0.008271093,"domain_scores_codex":[0.9997157,0.00002815426,0.00004161191,0.00003156334,0.00008369018,0.00009929873],"domain_scores_gemma":[0.9997576,0.00003208002,0.00005466737,0.00004265167,0.0000471228,0.00006590013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003375797,0.00002189656,0.001089663,0.00007815917,0.000005870475,0.0002523483,0.00003827866,0.00003266432,0.9954065,0.0005628641,0.00005022713,0.002124006],"study_design_scores_gemma":[0.00005843437,0.0002369686,0.05807063,0.00003104438,0.00003672421,0.001878866,0.0002057247,0.0006107023,0.9342901,0.0003435898,0.004225311,0.00001190926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925794,0.002620043,0.001549615,0.0001037605,0.00003222322,0.00001741397,0.0002858608,0.00002782946,0.002783983],"genre_scores_gemma":[0.9945938,0.000881048,0.001708902,0.00002253485,0.00001227014,0.00003960633,0.0003545618,0.00001154494,0.00237583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002047877,"threshold_uncertainty_score":0.004517674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01271690307132177,"score_gpt":0.2245256074682929,"score_spread":0.2118087043969711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}