{"id":"W3126794321","doi":"10.1212/wnl.94.15_supplement.2906","title":"Two-year results of the Phase IIIb CHORDS study evaluating ocrelizumab effectiveness and safety in patients with relapsing-remitting multiple sclerosis who had a suboptimal response with prior disease-modifying therapy (2906)","year":2020,"lang":"en","type":"article","venue":"Neurology","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Ocrelizumab; Medicine; Relapsing remitting; Multiple sclerosis; Oncology; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005533527,0.0008185394,0.00161513,0.0002639571,0.0006145522,0.001010545,0.0005326533,0.001393512,0.002672695],"category_scores_gemma":[0.005475926,0.0004175551,0.001868968,0.0003234161,0.0003753432,0.0009184238,0.000542963,0.002389868,0.0006912279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008938952,"about_ca_system_score_gemma":0.001421662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002172856,"about_ca_topic_score_gemma":0.005621028,"domain_scores_codex":[0.9985551,0.0006857606,0.0001658615,0.0001842944,0.0002057973,0.0002031792],"domain_scores_gemma":[0.9959207,0.0007231542,0.0009763797,0.0004243712,0.0007208125,0.00123464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8266414,0.01004802,0.08803977,0.0009123892,0.009382343,0.0002542949,0.0002233609,0.0007637618,0.007081033,0.0002412053,0.01161281,0.04479953],"study_design_scores_gemma":[0.4181577,0.1707033,0.3869135,0.0001944928,0.007218855,0.0005777996,0.0001487959,0.0006051823,0.003097403,0.000346081,0.01191725,0.0001195811],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9683985,0.008382356,0.0005540369,0.001239672,0.0003552128,0.002061584,0.01378043,0.00007313522,0.005155053],"genre_scores_gemma":[0.968407,0.001637717,0.001445779,0.002514071,0.0003079167,0.001255149,0.02035394,0.00002816494,0.004050352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005533527,"threshold_uncertainty_score":0.02926445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06202812811389533,"score_gpt":0.3359490088855747,"score_spread":0.2739208807716793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}