{"id":"W3126804828","doi":"10.1093/molbev/msab020","title":"The <i>Mastigamoeba balamuthi</i> Genome and the Nature of the Free-Living Ancestor of <i>Entamoeba</i>","year":2021,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; University of Alberta","funders":"Univerzita Karlova v Praze; Grantová Agentura České Republiky; Biotechnology and Biological Sciences Research Council; European Regional Development Fund; Horizon 2020 Framework Programme; Universiteit Gent","keywords":"Biology; Lineage (genetic); Entamoeba; Gene; Most recent common ancestor; Genome; Adaptation (eye); Phylogenetics; Horizontal gene transfer; Evolutionary biology; Entamoeba histolytica; Genetics; Phylogenetic tree; Gene family","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001019792,0.0003549857,0.0002209282,0.000532907,0.0004918494,0.0004824729,0.0002776191,0.0004524978,0.0006005278],"category_scores_gemma":[0.0002630587,0.0001819926,0.0003049076,0.0007428072,0.0002754222,0.0005150069,0.0003857397,0.0005714415,0.0002172679],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002431647,"about_ca_system_score_gemma":0.0003211633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002822374,"about_ca_topic_score_gemma":0.004208146,"domain_scores_codex":[0.9999095,0.000007584066,0.000005049904,0.00003925935,0.00001798019,0.00002059264],"domain_scores_gemma":[0.9998347,0.00002543614,0.00007030314,0.0000164941,0.00002728155,0.00002571831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002060822,0.00003953131,0.02999377,0.000341602,0.00004193096,0.0002479713,0.000629287,0.0002887627,0.9523638,0.0003550897,0.0002270873,0.01526511],"study_design_scores_gemma":[0.00002112247,0.0003294373,0.9112619,0.0001285789,0.0002059106,0.001519519,0.001402065,0.001908183,0.05775386,0.0008376119,0.02458864,0.00004326959],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991511,0.002403102,0.001925528,0.0001633411,0.00001798993,0.00001961173,0.002542138,0.00008573376,0.001331574],"genre_scores_gemma":[0.9768785,0.00219377,0.007121395,0.0002269182,0.00002623019,0.00005369319,0.01206047,0.00004341557,0.001395631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002822374,"threshold_uncertainty_score":0.005611956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002840487053465512,"score_gpt":0.2303050230082487,"score_spread":0.2274645359547832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}