{"id":"W3126804828","doi":"10.1093/molbev/msab020","title":"The <i>Mastigamoeba balamuthi</i> Genome and the Nature of the Free-Living Ancestor of <i>Entamoeba</i>","year":2021,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; University of Alberta","funders":"Univerzita Karlova v Praze; Grantová Agentura České Republiky; Biotechnology and Biological Sciences Research Council; European Regional Development Fund; Horizon 2020 Framework Programme; Universiteit Gent","keywords":"Biology; Lineage (genetic); Entamoeba; Gene; Most recent common ancestor; Genome; Adaptation (eye); Phylogenetics; Horizontal gene transfer; Evolutionary biology; Entamoeba histolytica; Genetics; Phylogenetic tree; Gene family","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002128369,0.000075187,0.0001481164,0.00001447631,0.0002335852,0.00000385472,0.00005893479,0.0001273351,0.000003843875],"category_scores_gemma":[0.0002475755,0.0000339216,0.00007237,0.000130955,0.0006993728,0.00001434731,0.0001119395,0.0001793163,3.802132e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001841267,"about_ca_system_score_gemma":0.00005739839,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006010788,"about_ca_topic_score_gemma":0.00003306081,"domain_scores_codex":[0.9993993,0.0001632753,0.000138161,0.0001301684,0.0000624585,0.0001066476],"domain_scores_gemma":[0.9993915,0.0001261115,0.00008904073,0.0002854355,0.00008690527,0.00002104055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002996826,0.0001821573,0.6158975,0.00009644982,0.0006806793,0.00001216549,0.0004451485,0.00001345995,0.2510488,0.129485,0.0001993206,0.001639628],"study_design_scores_gemma":[0.00338455,0.0002698645,0.954805,0.000144955,0.0005584446,0.0003808734,0.00049492,0.0002348246,0.02080674,0.01584621,0.002949241,0.0001244115],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9743416,0.0209435,0.001381115,0.001837036,0.0002197002,0.0001988457,0.00001387703,0.000005887368,0.001058436],"genre_scores_gemma":[0.9990271,0.0003730845,0.000121948,0.000275654,0.00002748904,0.00001080834,0.000006636365,0.000004387427,0.0001529047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3389074,"threshold_uncertainty_score":0.2576868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002840487053465512,"score_gpt":0.2303050230082487,"score_spread":0.2274645359547832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}