{"id":"W3126805840","doi":"10.1242/jcs.254359","title":"Vimentin tunes cell migration on collagen by controlling β1 integrin activation and clustering","year":2021,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Vimentin; Paxillin; Integrin; Focal adhesion; Cell biology; Cell migration; Biology; Intermediate Filament Protein; CDC42; Intermediate filament; Signal transducing adaptor protein; Cell adhesion; Cytoskeleton; Phosphorylation; Actin; Cell; Immunology; Biochemistry; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000294562,0.000055735,0.00006965164,0.00004475865,0.0001030261,0.00008539134,0.00008311402,0.00003295238,0.00001508573],"category_scores_gemma":[0.00006289723,0.00004853876,0.00003683726,0.0001003002,0.00002585532,0.00001893627,0.00004026688,0.00005985525,0.000001096787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002118856,"about_ca_system_score_gemma":0.00009412499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004059119,"about_ca_topic_score_gemma":0.00000899693,"domain_scores_codex":[0.999435,0.0000231687,0.0001653057,0.0001269847,0.0001557156,0.00009381137],"domain_scores_gemma":[0.9994891,0.00001318671,0.0001691162,0.00007620431,0.0001963236,0.00005608282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003181594,0.00004412946,0.00002623518,0.000003939934,0.000003105443,0.000001545453,0.0000500892,0.0001192879,0.9988058,0.000007754816,0.0004620491,0.0004442144],"study_design_scores_gemma":[0.0002770673,0.0002291017,0.00003242166,0.00001851419,0.000006542922,0.00001644583,0.0002700749,0.002598782,0.9819568,0.0000152893,0.01452718,0.00005176903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764839,0.0002887509,0.02157751,0.0003299042,0.0001986522,0.00003595549,0.000001403245,0.000001009017,0.001082901],"genre_scores_gemma":[0.9980574,0.0002725387,0.0006160784,0.0001666885,0.00007647039,6.730415e-7,0.000003741173,0.000003967556,0.0008024746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02157346,"threshold_uncertainty_score":0.1979353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00590479330995334,"score_gpt":0.2316770252364525,"score_spread":0.2257722319264992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}