{"id":"W3126869189","doi":"10.1016/j.hoc.2020.09.005","title":"Advanced Melanoma","year":2020,"lang":"en","type":"review","venue":"Hematology/Oncology Clinics of North America","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Bristol-Myers Squibb Canada; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; Merck; Bristol-Myers Squibb","keywords":"Melanoma; Acquired resistance; Medicine; Innate immune system; Metastatic melanoma; Cancer research; Immunology; Cancer; Immune system; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001635044,0.0006802334,0.0005529836,0.001077072,0.0002501946,0.0006227342,0.0004085193,0.0006608694,0.01544657],"category_scores_gemma":[0.0003609909,0.0001478565,0.000296353,0.0006414357,0.0001844244,0.0005102458,0.0005468011,0.001336223,0.008910024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003358595,"about_ca_system_score_gemma":0.0004950924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009327871,"about_ca_topic_score_gemma":0.003390618,"domain_scores_codex":[0.9999298,0.000009568444,0.000005065732,0.00001791903,0.00002427946,0.000013388],"domain_scores_gemma":[0.9999082,0.00002170748,0.00001418201,0.000006101601,0.00002531276,0.00002447475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004934026,0.00003508057,0.000167933,0.001717553,0.00001818634,0.0002330772,0.00001077472,0.00009889802,0.001193604,0.001278208,0.1118274,0.88337],"study_design_scores_gemma":[0.00002877633,0.00006092036,0.0007599303,0.001154588,0.00004020742,0.002229588,0.00001530226,0.00006901964,0.0004334303,0.0006885715,0.9945135,0.000006111854],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004489889,0.9733143,0.0005737181,0.0009123281,0.001946049,0.0000316984,0.0001110746,0.00008090957,0.02258091],"genre_scores_gemma":[0.005630039,0.9561014,0.0009273994,0.00229628,0.001639804,0.0000407337,0.0004494463,0.00001374822,0.03290112],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01544657,"threshold_uncertainty_score":0.05167395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03186428674690726,"score_gpt":0.3485917963956079,"score_spread":0.3167275096487006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}