{"id":"W3126896508","doi":"10.1007/s42242-020-00114-3","title":"Peptides-based vaccine against SARS-nCoV-2 antigenic fragmented synthetic epitopes recognized by T cell and β-cell initiation of specific antibodies to fight the infection","year":2021,"lang":"en","type":"article","venue":"Bio-Design and Manufacturing","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Umm Al-Qura University","keywords":"Epitope; Virology; Antigen; Peptide vaccine; Antibody; Biology; Peptide; Epitope mapping; Monoclonal antibody; Coronavirus; Immunology; Computational biology; Coronavirus disease 2019 (COVID-19); Medicine; Disease; Infectious disease (medical specialty); Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004006697,0.0002200561,0.0003431308,0.000206138,0.0001768986,0.00007364944,0.0000687297,0.0001032623,0.00001864923],"category_scores_gemma":[0.00006820803,0.0001643972,0.00007976617,0.0001713716,0.00005062113,0.00008585355,0.00006949389,0.0001886659,0.00001458516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005216201,"about_ca_system_score_gemma":0.00009120369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000072646,"about_ca_topic_score_gemma":0.00001332219,"domain_scores_codex":[0.9985446,0.0001833806,0.0003192311,0.0004116464,0.0002583902,0.0002827621],"domain_scores_gemma":[0.9991359,0.0003189701,0.0001078701,0.0002833123,0.00009919893,0.00005477852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003803998,0.0001726372,0.003408363,0.0003552559,0.00003662514,0.00002871868,0.0002087294,0.000005789244,0.9836669,0.000001403416,0.001235427,0.01049978],"study_design_scores_gemma":[0.00191647,0.0002598993,0.008827709,0.0002173492,0.00005862644,0.00001044903,0.00008702641,0.0002185368,0.9686046,0.00003487962,0.01959044,0.0001740157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901958,0.002151343,0.005780934,0.0005278807,0.00009577844,0.0006945556,0.00001144537,0.00004987187,0.0004923567],"genre_scores_gemma":[0.9941252,0.001079572,0.0008393015,0.003758175,0.00006553414,0.00002339684,0.00001938244,0.00002887115,0.00006054259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01835501,"threshold_uncertainty_score":0.6703925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03094050998513892,"score_gpt":0.2836346183156204,"score_spread":0.2526941083304814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}