{"id":"W3126896508","doi":"10.1007/s42242-020-00114-3","title":"Peptides-based vaccine against SARS-nCoV-2 antigenic fragmented synthetic epitopes recognized by T cell and β-cell initiation of specific antibodies to fight the infection","year":2021,"lang":"en","type":"article","venue":"Bio-Design and Manufacturing","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Umm Al-Qura University","keywords":"Epitope; Virology; Antigen; Peptide vaccine; Antibody; Biology; Peptide; Epitope mapping; Monoclonal antibody; Coronavirus; Immunology; Computational biology; Coronavirus disease 2019 (COVID-19); Medicine; Disease; Infectious disease (medical specialty); Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001385494,0.0003464473,0.0001536687,0.0001473854,0.000104756,0.000174154,0.0001968491,0.0002641532,0.001395127],"category_scores_gemma":[0.0001017202,0.0001233605,0.0001949397,0.00007597594,0.0001069448,0.0001348644,0.0001756235,0.0005594749,0.000426614],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002032358,"about_ca_system_score_gemma":0.0001950328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002434628,"about_ca_topic_score_gemma":0.0003499093,"domain_scores_codex":[0.9999213,0.00001268908,0.000004917303,0.00001636728,0.00001891251,0.00002577785],"domain_scores_gemma":[0.9999635,0.000004420295,0.000007524986,0.00000321529,0.000009191765,0.00001214936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001872359,0.00009861664,0.0001217909,0.00004053469,0.000008806865,0.00003969555,0.00001284868,0.0007457802,0.9951133,0.0002000461,0.000118538,0.00331288],"study_design_scores_gemma":[0.0002424812,0.002836903,0.002361634,0.00002082313,0.00004666439,0.000389923,0.00003770812,0.004391039,0.9794371,0.0002368948,0.009990651,0.000008171908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847921,0.001121088,0.01016699,0.0001323126,0.0001552022,0.000197034,0.0003213629,0.00005852331,0.00305533],"genre_scores_gemma":[0.9897795,0.0005569365,0.005578016,0.0001502925,0.00002554454,0.00009490868,0.0007223427,0.00001125211,0.003081255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001395127,"threshold_uncertainty_score":0.004667222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03094050998513892,"score_gpt":0.2836346183156204,"score_spread":0.2526941083304814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}