{"id":"W3126990883","doi":"10.1101/2021.01.28.428724","title":"Resident Cardiac Macrophages Mediate Adaptive Myocardial Remodeling","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network","funders":"National Institutes of Health; Office of Research Infrastructure Programs, National Institutes of Health; Center for Cellular Imaging, Washington University; Children's Discovery Institute; NIH Office of the Director; National Heart, Lung, and Blood Institute; Foundation for Barnes-Jewish Hospital","keywords":"CCR2; Macrophage; Inflammation; Chemokine; Cell biology; Contractility; Heart failure; Population; Myocyte; Angiogenesis; Chemokine receptor; Biology; Medicine; Immunology; Cancer research; Internal medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003506227,0.0002755052,0.0001647236,0.0001556475,0.0001214392,0.0002852975,0.0001107698,0.0002206686,0.002048447],"category_scores_gemma":[0.0001460198,0.00007550208,0.0001086345,0.00005106522,0.0002358442,0.0001957273,0.000322494,0.0003804869,0.000566553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001052906,"about_ca_system_score_gemma":0.0001211869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001010675,"about_ca_topic_score_gemma":0.00008043372,"domain_scores_codex":[0.9999046,0.0000238294,0.000005128846,0.00001716591,0.00001982691,0.00002942123],"domain_scores_gemma":[0.9999362,0.00000890991,0.00001284565,0.000008207755,0.00001125071,0.00002262632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002704802,0.00004141217,0.002072494,0.0001294138,0.0000114163,0.0005557305,0.00009448211,0.0001926972,0.9837066,0.003214103,0.0009654658,0.008745679],"study_design_scores_gemma":[0.0002261515,0.0009123997,0.04211684,0.000139118,0.00008767586,0.004768223,0.0004734792,0.006126474,0.8881519,0.01225539,0.04471695,0.00002549781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9644266,0.01167728,0.0129955,0.001364772,0.0002865735,0.00004209861,0.000250293,0.0001699379,0.008786904],"genre_scores_gemma":[0.9915094,0.001847478,0.001879104,0.0002129731,0.0001861693,0.00003101914,0.000158857,0.00001269238,0.004162347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002048447,"threshold_uncertainty_score":0.006852686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01772856019926371,"score_gpt":0.2369001472533947,"score_spread":0.219171587054131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}