{"id":"W3126990883","doi":"10.1101/2021.01.28.428724","title":"Resident Cardiac Macrophages Mediate Adaptive Myocardial Remodeling","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network","funders":"National Institutes of Health; Office of Research Infrastructure Programs, National Institutes of Health; Center for Cellular Imaging, Washington University; Children's Discovery Institute; NIH Office of the Director; National Heart, Lung, and Blood Institute; Foundation for Barnes-Jewish Hospital","keywords":"CCR2; Macrophage; Inflammation; Chemokine; Cell biology; Contractility; Heart failure; Population; Myocyte; Angiogenesis; Chemokine receptor; Biology; Medicine; Immunology; Cancer research; Internal medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001284533,0.001075778,0.002295162,0.000452021,0.0002908313,0.0004143574,0.0003966186,0.001255515,0.00006863281],"category_scores_gemma":[0.0004034554,0.001098929,0.001587219,0.0006066389,0.000180015,0.0001935696,0.001162836,0.002110872,0.00007397887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007956636,"about_ca_system_score_gemma":0.002112363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002361785,"about_ca_topic_score_gemma":0.000001744446,"domain_scores_codex":[0.9939858,0.0003565064,0.001161208,0.002065514,0.001344395,0.001086616],"domain_scores_gemma":[0.994603,0.0001222935,0.000524649,0.002396515,0.001567453,0.0007860492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002978283,0.0001434573,0.005042367,0.0009807283,0.001854039,0.0004311277,0.0000876316,0.003134448,0.9865571,0.0001056335,0.00134673,0.00001897125],"study_design_scores_gemma":[0.00430615,0.0004095116,0.3385267,0.01060093,0.006756997,6.491002e-7,0.000215873,0.02927928,0.5966355,0.000005854011,0.007982516,0.005280059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9633365,0.02539387,0.001892731,0.0004363749,0.00632677,0.001476376,0.0003739835,0.0006654722,0.0000979102],"genre_scores_gemma":[0.9764529,0.005860058,0.0127292,0.0003446307,0.004045852,0.0001712621,0.000003606277,0.0003678279,0.00002462247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3899215,"threshold_uncertainty_score":0.9991461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01772856019926371,"score_gpt":0.2369001472533947,"score_spread":0.219171587054131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}