{"id":"W3127013644","doi":"10.1016/s0140-6736(21)00219-1","title":"Posaconazole versus voriconazole for primary treatment of invasive aspergillosis: a phase 3, randomised, controlled, non-inferiority trial","year":2021,"lang":"en","type":"article","venue":"The Lancet","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":276,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Juravinski Hospital","funders":"","keywords":"Medicine; Voriconazole; Posaconazole; Aspergillosis; Clinical endpoint; Population; Internal medicine; Randomized controlled trial; Surgery; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004107577,0.0001851558,0.001518706,0.00002423867,0.0001022413,0.0000164739,0.000112054,0.00008336548,0.0001225898],"category_scores_gemma":[0.0007908545,0.0001110256,0.000549974,0.0001138472,0.0001088187,0.00004868847,0.00002346008,0.00008813845,0.000009934388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001488795,"about_ca_system_score_gemma":0.0005669756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002861644,"about_ca_topic_score_gemma":0.00008212602,"domain_scores_codex":[0.9986497,0.000111159,0.0004402742,0.000272446,0.0002320059,0.0002943839],"domain_scores_gemma":[0.9975725,0.001256049,0.0001685667,0.0006510255,0.0002620361,0.00008982305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9643956,0.001617663,0.001875627,0.0001637751,0.0007584241,0.00003268491,0.0003185471,0.000001591318,0.02550511,0.0001729246,0.001252403,0.003905686],"study_design_scores_gemma":[0.957737,0.003259509,0.004224734,0.00004893577,0.0008950726,0.00000452877,0.0003291041,0.00006708539,0.03055398,0.0001254267,0.002638772,0.0001158296],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862578,0.001810563,0.0002258586,0.002065217,0.0005085453,0.003415779,0.0001942363,0.00002701593,0.005495021],"genre_scores_gemma":[0.9957217,0.0009087328,0.0003398967,0.0004122644,0.001238448,0.0004402136,0.0001113947,0.00001539444,0.0008119651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009463924,"threshold_uncertainty_score":0.4527491,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05231989497242499,"score_gpt":0.3470294259671293,"score_spread":0.2947095309947043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}