{"id":"W3127013644","doi":"10.1016/s0140-6736(21)00219-1","title":"Posaconazole versus voriconazole for primary treatment of invasive aspergillosis: a phase 3, randomised, controlled, non-inferiority trial","year":2021,"lang":"en","type":"article","venue":"The Lancet","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":276,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Juravinski Hospital","funders":"","keywords":"Medicine; Voriconazole; Posaconazole; Aspergillosis; Clinical endpoint; Population; Internal medicine; Randomized controlled trial; Surgery; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002982646,0.002250527,0.004849672,0.0003990796,0.000517805,0.001605743,0.001160171,0.002913778,0.008412962],"category_scores_gemma":[0.003564524,0.0007839855,0.004135753,0.0004966337,0.001810968,0.001598462,0.0004889565,0.005050633,0.00126107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001116078,"about_ca_system_score_gemma":0.001207427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001296186,"about_ca_topic_score_gemma":0.002599787,"domain_scores_codex":[0.9985794,0.0007648451,0.00008170486,0.0002576479,0.0001045908,0.0002118808],"domain_scores_gemma":[0.9982315,0.0008018184,0.0003604798,0.0001643117,0.0001038123,0.0003382655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9875009,0.001118138,0.0001498311,0.0008101379,0.001512025,0.00004477987,0.00004186245,0.0001977488,0.001066791,0.0001535882,0.0006259102,0.006778423],"study_design_scores_gemma":[0.9860741,0.01216993,0.0004153096,0.00004502072,0.0005109041,0.00002706533,0.00001319004,0.0001831623,0.00008044862,0.0002087347,0.0002618135,0.00001035553],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9564518,0.0245565,0.00224767,0.002966144,0.003209449,0.00438652,0.001557184,0.0002879674,0.00433665],"genre_scores_gemma":[0.9786614,0.006868605,0.002322549,0.002734738,0.0009994413,0.003587715,0.0008773223,0.00005223799,0.003895963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008412962,"threshold_uncertainty_score":0.02814412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05231989497242499,"score_gpt":0.3470294259671293,"score_spread":0.2947095309947043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}