{"id":"W3127079984","doi":"10.1371/journal.pone.0245827","title":"Sustained functional benefits after a single set of injections with abobotulinumtoxinA using a 2-mL injection volume in adults with cervical dystonia: 12-week results from a randomized, double-blind, placebo-controlled phase 3b study","year":2021,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ipsen; Ipsen Biopharmaceuticals","keywords":"Placebo; Medicine; Cervical dystonia; Spasmodic Torticollis; Botulinum toxin; Randomized controlled trial; Population; Physical therapy; Placebo-controlled study; Anesthesia; Internal medicine; Surgery; Double blind; Torticollis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004308797,0.0004319615,0.001846796,0.0003902002,0.0001327165,0.00004212425,0.00008451773,0.0003580104,0.0002580628],"category_scores_gemma":[0.0004939182,0.000301282,0.0002167687,0.001131159,0.0002365486,0.0001755115,0.00008464127,0.0008926623,0.000009632746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001612237,"about_ca_system_score_gemma":0.0003685018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006273492,"about_ca_topic_score_gemma":0.002349332,"domain_scores_codex":[0.9961993,0.000436383,0.001104463,0.0009057132,0.0008877952,0.0004663778],"domain_scores_gemma":[0.9976789,0.000579036,0.0003819085,0.000464388,0.0006642674,0.0002314707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9478496,0.03745611,0.003754635,0.0001164763,0.002451376,0.0006518853,0.002318078,0.003680554,0.001605731,0.000007139311,0.000007251232,0.0001011091],"study_design_scores_gemma":[0.960219,0.01064531,0.002883755,0.001071027,0.003219756,0.0001040928,0.003295741,0.01735099,0.0008110877,0.00004579522,0.000001771922,0.0003516298],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924316,0.000353059,0.0003784374,0.001125598,0.00006929762,0.005026425,0.0001050456,0.0001150975,0.0003953772],"genre_scores_gemma":[0.997115,0.00004456814,0.001179789,0.0001866112,0.0001483698,0.0006236551,0.0002363159,0.00006208594,0.0004036337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0268108,"threshold_uncertainty_score":0.9999439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05445521924241397,"score_gpt":0.2573435997660153,"score_spread":0.2028883805236014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}