{"id":"W3127159106","doi":"10.1093/neuonc/noab034","title":"Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q","year":2021,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institutes of Health","keywords":"Loss function; Internal medicine; Ependymoma; Cytogenetics; Biology; Weight loss; Oncology; Risk stratification; Chromosome; Methylation; Gastroenterology; Medicine; Genetics; Pathology; Gene; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000303464,0.0002391741,0.0003560403,0.0003401499,0.0003480144,0.000414127,0.0002121415,0.0002415384,0.00167365],"category_scores_gemma":[0.001143552,0.00009669449,0.0002169603,0.000479586,0.0003953499,0.0002688332,0.0005487443,0.0003146695,0.0001960856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002232748,"about_ca_system_score_gemma":0.0001836339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008325152,"about_ca_topic_score_gemma":0.001468824,"domain_scores_codex":[0.999795,0.00001829684,0.00001768407,0.00007431077,0.00005919556,0.0000354608],"domain_scores_gemma":[0.9995927,0.0001142063,0.0001476316,0.00004965521,0.00003106164,0.00006468717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001072233,0.00004756759,0.9219752,0.00008712865,0.0001445438,0.005035215,0.0001012072,0.0005207632,0.04218244,0.0001888248,0.0003778229,0.02826693],"study_design_scores_gemma":[0.00001599158,0.0001710677,0.9743407,0.00001034445,0.00005227185,0.02062254,0.00005816855,0.0003189792,0.003228179,0.0002741198,0.0009021835,0.000005467116],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977279,0.0004250529,0.0006220824,0.00003203359,0.000004976821,0.00001211784,0.0002868597,0.000015235,0.0008736734],"genre_scores_gemma":[0.9991059,0.0001190447,0.0003263331,0.00001381022,0.000005134606,0.000005509443,0.000255234,0.000002961856,0.0001660188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00167365,"threshold_uncertainty_score":0.005598903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01372833318397957,"score_gpt":0.2748075403027821,"score_spread":0.2610792071188026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}