{"id":"W3127186093","doi":"10.3389/fendo.2020.624122","title":"Role of the Orphan Nuclear Receptor NR4A Family in T-Cell Biology","year":2021,"lang":"en","type":"review","venue":"Frontiers in Endocrinology","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Faculty of Medicine and Dentistry, University of Alberta; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Alberta","keywords":"Neuron-derived orphan receptor 1; Nuclear receptor; Orphan receptor; Nerve growth factor IB; Transcription factor; Biology; Receptor; Chimeric antigen receptor; T-cell receptor; T cell; Cell biology; Cell; Gene; Cancer research; Genetics; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004621274,0.0006394126,0.0008272199,0.001251938,0.000261607,0.0007853396,0.0006363306,0.0008044526,0.002943038],"category_scores_gemma":[0.0004180512,0.000193567,0.0002822896,0.001477138,0.0004652815,0.001095487,0.0006735008,0.001417733,0.002206984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006228241,"about_ca_system_score_gemma":0.001117652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000743169,"about_ca_topic_score_gemma":0.001310206,"domain_scores_codex":[0.9998935,0.00001754855,0.00001577251,0.00002364541,0.00003396316,0.00001554177],"domain_scores_gemma":[0.9998302,0.00006896423,0.00002075278,0.000006756777,0.00004958508,0.00002372966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009616333,0.00003816761,0.0001714993,0.0104963,0.00005337864,0.0002943833,0.00007718515,0.0004568043,0.004069269,0.008647089,0.02931561,0.9462842],"study_design_scores_gemma":[0.00000968676,0.0000533818,0.0004039115,0.001446321,0.00004462382,0.0009968635,0.00004628458,0.00006079869,0.0005188216,0.002680537,0.9937252,0.00001352163],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001046769,0.9980702,0.0001526912,0.0002297658,0.0002386727,0.000001964727,0.00001528291,0.000005897045,0.001180845],"genre_scores_gemma":[0.0006134828,0.9983156,0.0001433905,0.0001334852,0.000166687,0.000003499943,0.00002792782,0.000001214322,0.0005947809],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002943038,"threshold_uncertainty_score":0.009845436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02959779117347253,"score_gpt":0.2771876708220158,"score_spread":0.2475898796485433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}