{"id":"W3127191784","doi":"10.26443/mjm.v3i2.544","title":"Commentary on MJM Crossroads: Human Germline Gene Therapy","year":2020,"lang":"en","type":"article","venue":"McGill Journal of Medicine","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Germline; Genetic enhancement; Gene; Cancer research; Oncology; Genetics; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009655044,0.001390321,0.002795118,0.001325063,0.006826573,0.005954469,0.005236916,0.1143354,0.01452294],"category_scores_gemma":[0.04984984,0.001286959,0.002985246,0.001212091,0.006682063,0.005936064,0.00411913,0.09075573,0.008182014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.009119275,"about_ca_system_score_gemma":0.01095745,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01748821,"about_ca_topic_score_gemma":0.03308171,"domain_scores_codex":[0.9908709,0.001766574,0.0009159552,0.001394954,0.003674231,0.001377358],"domain_scores_gemma":[0.9714991,0.01474373,0.001877149,0.0008579693,0.006042319,0.004979713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003582141,0.00000654354,0.00004548411,0.00005608926,0.000009461363,0.000142785,0.00003356575,0.00001675007,0.00006032266,0.001307413,0.9963698,0.001915923],"study_design_scores_gemma":[0.0001176335,0.00003841978,0.0004735726,0.000515417,0.00005199054,0.0003066417,0.0001519752,0.0000933327,0.0001495104,0.003906283,0.9941378,0.0000575151],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0001041787,0.003077256,0.00006179469,0.869141,0.1257783,0.000008994063,0.00003872357,0.00002116272,0.001768752],"genre_scores_gemma":[0.0009470714,0.0008875649,0.00006698704,0.9119401,0.08243633,0.00002714793,0.00001446434,0.00001937539,0.003661006],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1143354,"threshold_uncertainty_score":0.06616527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05579945320612604,"score_gpt":0.3589687175998916,"score_spread":0.3031692643937655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}