{"id":"W3127312455","doi":"10.1038/s41598-021-82499-4","title":"Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP)","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Malaria Research and Control","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de Santé Publique du Québec; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fonds Québécois de la Recherche sur la Nature et les Technologies; Science Foundation Ireland; Canada Foundation for Innovation","keywords":"Plasmodium falciparum; Aminopeptidase; Enzyme; Biochemistry; Cytosol; Biology; Leucyl aminopeptidase; Cell fractionation; Vacuole; Parasite hosting; Cytoplasm; Amino acid; Leucine; Malaria; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000964085,0.0001784236,0.0003516814,0.0001147304,0.0002335535,0.0001903004,0.00009129849,0.0001173426,0.0001722611],"category_scores_gemma":[0.00068977,0.0001267471,0.0001097221,0.0003633686,0.0006152093,0.0001361406,0.0001961457,0.0002420132,0.000006392597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003669912,"about_ca_system_score_gemma":0.0004209262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003784825,"about_ca_topic_score_gemma":0.00001076573,"domain_scores_codex":[0.9975044,0.00009967047,0.000524077,0.0007515461,0.000734943,0.0003853223],"domain_scores_gemma":[0.9980571,0.00005689443,0.0002524056,0.0009726534,0.0003383935,0.0003225985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007239026,0.0001356708,0.0189625,0.0001636173,0.00004150881,0.0006490677,0.0002377663,3.075966e-7,0.9743643,0.0001229306,0.003631694,0.001618265],"study_design_scores_gemma":[0.0009047921,0.00007588869,0.0807596,0.0001780533,0.0000958379,0.000926695,0.0001943956,0.0002757756,0.9074309,0.0003114773,0.0086896,0.0001569822],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943487,0.0007482237,0.00004303339,0.002225037,0.0008524073,0.0005186108,0.00001434865,0.00002369723,0.001225942],"genre_scores_gemma":[0.9904883,0.00001948998,0.0001319281,0.00009126733,0.00009530244,0.00002688114,0.00009029719,0.00001553002,0.009041023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06693338,"threshold_uncertainty_score":0.5168597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01406803834672455,"score_gpt":0.2444316328669165,"score_spread":0.230363594520192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}