{"id":"W3127312455","doi":"10.1038/s41598-021-82499-4","title":"Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP)","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Malaria Research and Control","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de Santé Publique du Québec; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fonds Québécois de la Recherche sur la Nature et les Technologies; Science Foundation Ireland; Canada Foundation for Innovation","keywords":"Plasmodium falciparum; Aminopeptidase; Enzyme; Biochemistry; Cytosol; Biology; Leucyl aminopeptidase; Cell fractionation; Vacuole; Parasite hosting; Cytoplasm; Amino acid; Leucine; Malaria; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001272126,0.0003405363,0.0001980261,0.000269863,0.0001715045,0.0003226047,0.0001427063,0.0002637807,0.0006077309],"category_scores_gemma":[0.0001666379,0.0001229609,0.0002050538,0.0002880336,0.0002744134,0.000271195,0.0001939886,0.0004461527,0.0004910935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002252799,"about_ca_system_score_gemma":0.0002178587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007461659,"about_ca_topic_score_gemma":0.000720892,"domain_scores_codex":[0.9998947,0.00001564607,0.000008374705,0.0000202724,0.00003211259,0.00002894653],"domain_scores_gemma":[0.9998722,0.00002783769,0.00002752308,0.0000183045,0.00002642579,0.00002764248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000371287,0.00000800846,0.0001529017,0.00004446802,0.000002420139,0.00004356544,0.00001485038,0.00001799742,0.9988526,0.00007078542,0.000009429337,0.0007458825],"study_design_scores_gemma":[0.00001081644,0.0003197464,0.01750707,0.0000112638,0.00002635338,0.001438081,0.0001210636,0.0005127203,0.9746789,0.0001124267,0.005255448,0.000006163232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9794257,0.007028356,0.009711435,0.0002275565,0.00002947429,0.00004284101,0.001003402,0.00003903457,0.002492159],"genre_scores_gemma":[0.9811175,0.003739643,0.009608204,0.00007311754,0.00002288827,0.00004398122,0.002573948,0.00002570657,0.002794952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007461659,"threshold_uncertainty_score":0.002033055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01406803834672455,"score_gpt":0.2444316328669165,"score_spread":0.230363594520192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}