{"id":"W3127330586","doi":"10.2147/ott.s291086","title":"Combination Therapy with iRGD-antiCD3 and PD-1 Blockade Enhances Antitumor Potency of Cord Blood-Derived T Cells","year":2021,"lang":"en","type":"article","venue":"OncoTargets and Therapy","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Education and Child Care","funders":"Government of Jiangsu Province; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China","keywords":"In vivo; Cancer research; Immune system; Tumor microenvironment; T cell; Immunotherapy; In vitro; Cytotoxic T cell; CD3; Antibody; Chemistry; Antigen; CD8; Medicine; Immunology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001489921,0.0004599559,0.0004343636,0.000251053,0.00008195479,0.000237842,0.000199238,0.0002051874,0.0008093459],"category_scores_gemma":[0.0001059126,0.00007003627,0.0002615985,0.0002437373,0.0001881319,0.0001282067,0.0001553659,0.0006094629,0.0002407271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002828263,"about_ca_system_score_gemma":0.0002656319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004315301,"about_ca_topic_score_gemma":0.0006613213,"domain_scores_codex":[0.999855,0.00002168897,0.00001497813,0.0000333247,0.00003187084,0.00004312158],"domain_scores_gemma":[0.9999133,0.00001206942,0.0000241746,0.00001186753,0.000009399178,0.00002911362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009052583,0.000340784,0.0005976666,0.0001491222,0.00002859707,0.0001094178,0.00003259631,0.0004784085,0.9825172,0.00008358968,0.0003178183,0.01443953],"study_design_scores_gemma":[0.000141133,0.003676215,0.003063162,0.00001443268,0.0000843021,0.0004603489,0.00001405241,0.001727652,0.9873169,0.00004051611,0.003454888,0.000006371596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928817,0.002793859,0.002101236,0.00008715154,0.00005114534,0.00006551496,0.0001749919,0.0001853323,0.001659203],"genre_scores_gemma":[0.9965766,0.0007838418,0.001628478,0.00005210308,0.0000228005,0.00005111876,0.0002221137,0.00001492407,0.0006480114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008093459,"threshold_uncertainty_score":0.002707541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01948952803681661,"score_gpt":0.2845316611152413,"score_spread":0.2650421330784247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}