{"id":"W3127353438","doi":"10.1007/s11356-021-12629-y","title":"In vitro estrogenic, cytotoxic, and genotoxic profiles of the xenoestrogens 8-prenylnaringenine, genistein and tartrazine","year":2021,"lang":"en","type":"article","venue":"Environmental Science and Pollution Research","topic":"Hops Chemistry and Applications","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Phytoestrogens; Xenoestrogen; Genistein; Genotoxicity; Estrogen; Chemistry; Micronucleus test; Paraben; Biology; Pharmacology; Toxicity; Endocrinology; Internal medicine; Estrogen receptor; Medicine; Food science; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001036714,0.00008500311,0.00009894727,0.00005737686,0.0005750973,0.00002333114,0.0001603453,0.00009145535,0.0001831222],"category_scores_gemma":[0.00006867004,0.00007040353,0.00001872017,0.0004092702,0.002608788,0.0001084392,0.000372934,0.0003964927,0.000005941119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007069698,"about_ca_system_score_gemma":0.000122778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001531592,"about_ca_topic_score_gemma":0.000007447721,"domain_scores_codex":[0.9987125,0.0001671712,0.0001627948,0.00032106,0.0003064907,0.0003300027],"domain_scores_gemma":[0.9995486,0.00007023748,0.00003620705,0.0001607913,0.00001876359,0.0001654623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003038315,0.00009555137,0.01029261,0.00001379224,0.00000642549,0.000005145867,0.0002425954,0.000006968398,0.9868419,0.0003777277,0.00005830505,0.002028651],"study_design_scores_gemma":[0.0003412933,0.00002342323,0.04354892,0.000004155592,0.000008404428,0.00006140689,0.0003124875,0.0003457064,0.9471714,0.0002139546,0.007902599,0.00006617421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958749,0.001399181,0.00000204022,0.001898297,0.00002687618,0.000251704,0.00008964356,0.000003988502,0.0004533537],"genre_scores_gemma":[0.9983416,0.0007381378,0.0001406959,0.0001961063,0.00003180296,0.00004316643,0.00000472615,0.000004370432,0.0004993917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03967037,"threshold_uncertainty_score":0.961219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08177231580253529,"score_gpt":0.4228801586678314,"score_spread":0.3411078428652961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}