{"id":"W3127404454","doi":"10.22541/au.158629966.69248955","title":"Pathogenesis of Beta-lactam-induced Serum Sickness-Like Reaction: The potential role of Reactive Drug Metabolites","year":2020,"lang":"en","type":"dataset","venue":"Authorea","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Culprit; Pathogenesis; Drug; Medicine; Pharmacology; Antibiotics; Metabolite; Immunology; Internal medicine; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002876415,0.0004148338,0.0003062043,0.0004388562,0.0001435944,0.0002697439,0.0001552409,0.0004015717,0.00138802],"category_scores_gemma":[0.0004625407,0.0001337648,0.0002120723,0.0001681951,0.0002610151,0.0002492447,0.0002046755,0.0002155105,0.0002441532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001162472,"about_ca_system_score_gemma":0.0001090971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000114905,"about_ca_topic_score_gemma":0.00007934403,"domain_scores_codex":[0.9998187,0.00007075104,0.00002515897,0.00002800692,0.00002702203,0.00003028044],"domain_scores_gemma":[0.9996821,0.00006383099,0.0001731271,0.00001443374,0.00002724609,0.0000392362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002953159,0.000572484,0.7007813,0.0004327291,0.00007834147,0.02214996,0.0004500488,0.0002947515,0.2508666,0.000350676,0.0002330712,0.02083682],"study_design_scores_gemma":[0.0001480069,0.00618946,0.8896417,0.00006396314,0.0001010988,0.05798053,0.0004120233,0.001589378,0.04184862,0.0002727883,0.001735424,0.00001696082],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"dataset","genre_scores_codex":[0.9970173,0.001946597,0.0004632615,0.0000530677,0.000006570805,0.0000272484,0.00003193092,0.00001371806,0.0004405147],"genre_scores_gemma":[0.9993619,0.0003041037,0.0001767225,0.00002275229,0.00001475254,0.000006074835,0.00003950805,6.531305e-7,0.0000735575],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.00138802,"threshold_uncertainty_score":0.004643381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01103271663948984,"score_gpt":0.2568238400409557,"score_spread":0.2457911234014658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}