{"id":"W3127411251","doi":"10.1016/j.impact.2021.100299","title":"Protein-bound uremic toxins (PBUTs) in chronic kidney disease (CKD) patients: Production pathway, challenges and recent advances in renal PBUTs clearance","year":2021,"lang":"en","type":"review","venue":"NanoImpact","topic":"Dialysis and Renal Disease Management","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Paul's Hospital; University of Saskatchewan","funders":"Saskatchewan Health Research Foundation","keywords":"Uremic toxins; Uremia; Chemistry; Kidney disease; Biochemistry; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004867176,0.0006035556,0.001831273,0.0005269711,0.0000565801,0.00005795864,0.000156989,0.0002157108,0.00008473376],"category_scores_gemma":[0.0008368726,0.0004477761,0.0003572397,0.0006902214,0.00009145049,0.0002638421,0.0001289996,0.0005229898,0.00002154833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001417121,"about_ca_system_score_gemma":0.00159781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000013959,"about_ca_topic_score_gemma":0.0001507201,"domain_scores_codex":[0.9964303,0.0003831655,0.0008712874,0.001105564,0.0006376291,0.0005721012],"domain_scores_gemma":[0.9981962,0.00002747971,0.0004026177,0.0006642736,0.0001199775,0.0005893795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001692117,0.0008186721,0.00004910807,0.03043736,0.0001323496,0.0001606609,0.00007920722,0.000008511967,0.000009825028,0.00006967915,0.0002684326,0.967797],"study_design_scores_gemma":[0.001244434,0.0002741626,0.002543346,0.08290035,0.0005036861,0.000004834391,0.00002081662,0.000007030967,0.000007521335,0.00003521019,0.9120338,0.0004247896],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001933415,0.9926204,8.174316e-7,0.0005647363,0.0003112102,0.003517466,0.00008792941,0.00003874341,0.0009252706],"genre_scores_gemma":[0.001356342,0.9965821,0.00001659125,0.00008562812,0.0004469165,0.0004883588,0.0005276267,0.00007338966,0.0004230394],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9673722,"threshold_uncertainty_score":0.9997974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03201701844601498,"score_gpt":0.3144580510972769,"score_spread":0.2824410326512619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}