{"id":"W3127557341","doi":"10.1139/bcb-2020-0593","title":"The endless battle between phages and CRISPR–Cas systems in <i>Streptococcus thermophilus</i>","year":2021,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Streptococcus thermophilus; Biology; Mobile genetic elements; Biogenesis; Plasmid; Genome; Cas9; Trans-activating crRNA; Computational biology; Bacteriophage; Streptococcus pyogenes; Genetics; Genome editing; Bacteria; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004195509,0.0005772581,0.0008521448,0.00148902,0.0002080961,0.0007201761,0.0004820723,0.0009073793,0.001705624],"category_scores_gemma":[0.0003808509,0.0002667072,0.0003868771,0.001627778,0.0003165989,0.001122111,0.0005003166,0.001555316,0.001331562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005334065,"about_ca_system_score_gemma":0.001057639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001006122,"about_ca_topic_score_gemma":0.001458762,"domain_scores_codex":[0.9998536,0.00002255889,0.00002185882,0.00002524994,0.00006198895,0.00001482178],"domain_scores_gemma":[0.9998511,0.00006901337,0.00002277326,0.000005609498,0.0000353836,0.00001606072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004335076,0.00003432737,0.00009429613,0.01815104,0.0000548075,0.0001742669,0.00006755353,0.0003907611,0.006404064,0.006585205,0.02649353,0.9415067],"study_design_scores_gemma":[0.000005278665,0.00007096169,0.000394693,0.001802649,0.00003975761,0.0006042937,0.00002922233,0.00006235203,0.001228335,0.00133281,0.9944149,0.0000146209],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001829996,0.9972878,0.0003097863,0.0003684197,0.0003047776,0.000004884203,0.00002341876,0.00001309531,0.001504894],"genre_scores_gemma":[0.0007566941,0.9972702,0.0003786068,0.0003169595,0.000146942,0.000007915156,0.00005062765,0.000002940785,0.001069041],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001705624,"threshold_uncertainty_score":0.005705833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01483823662273085,"score_gpt":0.3302251451864426,"score_spread":0.3153869085637117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}