{"id":"W3127599355","doi":"10.1016/j.annonc.2021.01.075","title":"Combined small-cell lung carcinoma revealed to be an intratumoural metastasis by genetic analysis","year":2021,"lang":"en","type":"letter","venue":"Annals of Oncology","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre; McGill Genome Centre; McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research; Pfizer Canada; Amgen Canada; Bristol-Myers Squibb Canada; National Institutes of Health; Merck Canada; Canada Foundation for Innovation; Advanced Accelerator Applications; Clovis Oncology; Fondation de l'Hôpital Général de Montréal; McMaster University; GlaxoSmithKline; Cancer Research Society; American Surgical Association Foundation; Leon Lowenstein Foundation; March of Dimes Foundation; F. Hoffmann-La Roche; Roche; Samsung; Genentech; Merck; California Institute for Regenerative Medicine; Fonds de Recherche du Québec - Santé; L'Oreal USA; AstraZeneca; Prostate Cancer Foundation; Amgen","keywords":"Medicine; Adenocarcinoma; Carcinoma; Small-cell carcinoma; Large cell; Lung; Pathology; Small Cell Lung Carcinoma; Metastasis; Oncology; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005948874,0.0005032761,0.00276113,0.0008839049,0.00007603045,0.00002890556,0.0005219381,0.0007092757,0.0004047954],"category_scores_gemma":[0.0003308531,0.0004580603,0.0006901462,0.001429829,0.0002373464,0.00004375845,0.0003665327,0.00153613,0.000009208273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000300282,"about_ca_system_score_gemma":0.001103345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001300809,"about_ca_topic_score_gemma":0.0005158519,"domain_scores_codex":[0.9955204,0.0008913379,0.0008793724,0.0009557141,0.0007510201,0.001002163],"domain_scores_gemma":[0.9964098,0.0004204013,0.0004069726,0.001118549,0.001247479,0.0003968531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003262377,0.000360562,0.008243309,0.0008488783,0.005964399,0.00310925,0.0005123909,0.000004948298,0.00208447,0.000002269182,0.977237,0.001306274],"study_design_scores_gemma":[0.003504005,0.01411612,0.02639169,0.000132226,0.01391434,0.00007217577,0.0004855764,0.0001043135,0.009366347,0.00003799324,0.9310207,0.000854547],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.3125966,0.004842119,0.00003005496,0.6797144,0.0001856976,0.0008877716,0.0003539776,0.00004882178,0.001340534],"genre_scores_gemma":[0.1523388,0.001747635,0.002162323,0.8328046,0.001368161,0.0003462867,0.002255514,0.0001565047,0.006820234],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1602578,"threshold_uncertainty_score":0.9997871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1112573168191713,"score_gpt":0.406147336166251,"score_spread":0.2948900193470797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}