{"id":"W3127633650","doi":"10.1021/acs.jpcb.1c00954","title":"A Simple Explicit-Solvent Model of Polyampholyte Phase Behaviors and Its Ramifications for Dielectric Effects in Biomolecular Condensates","year":2021,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry B","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Canada Research Chairs; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Dielectric; Chemical physics; Phase (matter); Dipole; Electrostatics; Intrinsically disordered proteins; Polarizability; Random phase approximation; Solvent; Chemistry; Permittivity; Biomolecule; Relative permittivity; Materials science; Condensed matter physics; Molecule; Nanotechnology; Physics; Physical chemistry; Organic chemistry; Optoelectronics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000180697,0.0005562119,0.0007771194,0.0004341321,0.000551002,0.0006746173,0.001235623,0.001567504,0.002002939],"category_scores_gemma":[0.0006747268,0.0002924925,0.0007778714,0.0004462879,0.00106262,0.001192354,0.0005875124,0.0007367342,0.0003362587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006872293,"about_ca_system_score_gemma":0.0009643261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009920374,"about_ca_topic_score_gemma":0.004614868,"domain_scores_codex":[0.9999056,0.00002206389,0.000005263669,0.00001730659,0.00002403139,0.00002569312],"domain_scores_gemma":[0.999777,0.00008746978,0.00003420583,0.00002521033,0.00003683273,0.00003930689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00008357713,0.00009456495,0.0005558177,0.00009511178,0.00001759421,0.0003665083,0.00008756645,0.9257245,0.01469661,0.05644532,0.0002765828,0.001556253],"study_design_scores_gemma":[0.00002774511,0.0000282051,0.0001290226,0.000006820611,0.00000730005,0.00002122626,0.0000151158,0.9950548,0.0007006217,0.003560362,0.000439845,0.000008804398],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7703417,0.002230636,0.1934621,0.001797138,0.000252521,0.0001597721,0.000827916,0.0002545207,0.0306737],"genre_scores_gemma":[0.968142,0.001271833,0.01843533,0.000246149,0.00007930454,0.0002612251,0.0002967321,0.00006791802,0.01119943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009920374,"threshold_uncertainty_score":0.01972526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01599012104427029,"score_gpt":0.3174374479752622,"score_spread":0.301447326930992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}