{"id":"W3127767560","doi":"10.1101/2021.02.02.429403","title":"AN INULIN-TYPE FRUCTAN ENRICHED EXCLUSIVE ENTERAL NUTRITION FORMULA SUPPRESSES COLITIS THROUGH GUT MICROBIOME MODULATION AND PROMOTING EXPANSION OF ANTI-INFLAMMATORY T CELL SUBSETS","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Microbial Metabolites in Food Biotechnology","field":"Nursing","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; CH.I.L.D. Foundation; Crohn's and Colitis Canada; Michael Smith Health Research BC","keywords":"Colitis; Inflammatory bowel disease; FOXP3; Enteral administration; Immune system; Immunology; Ulcerative colitis; Bacteroides; Medicine; Gut flora; Bifidobacterium; Butyrate; Gastroenterology; Internal medicine; Lactobacillus; Biology; Disease; Parenteral nutrition","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001095131,0.0003951644,0.0004556415,0.0002563068,0.000132985,0.0002775545,0.0002609914,0.0002386536,0.001153388],"category_scores_gemma":[0.00008574565,0.000116939,0.0002235638,0.0001441364,0.0001964631,0.0002350067,0.0001991497,0.0007096582,0.0001381111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001759728,"about_ca_system_score_gemma":0.0002767692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000305337,"about_ca_topic_score_gemma":0.0005958998,"domain_scores_codex":[0.9999107,0.00001438232,0.000009272056,0.00001764674,0.00002203471,0.00002588918],"domain_scores_gemma":[0.9999207,0.000004772561,0.00002799081,0.000005236936,0.000007994059,0.00003328956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002889365,0.001353795,0.000521694,0.0001500621,0.00003429069,0.00005062218,0.00001510715,0.0001072294,0.987535,0.00006909401,0.0001068856,0.007166834],"study_design_scores_gemma":[0.001056985,0.02609644,0.0139932,0.00007570006,0.0003284109,0.0003778447,0.0001132518,0.001731184,0.9496846,0.0001310852,0.006390679,0.00002060295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972947,0.0007434093,0.0009870859,0.0001008015,0.00004700806,0.00004635542,0.0001796384,0.00003122903,0.0005697615],"genre_scores_gemma":[0.9927109,0.00115804,0.002787171,0.0001298398,0.00003026067,0.00009424143,0.0003571808,0.00001292328,0.002719485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001153388,"threshold_uncertainty_score":0.003858447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0100774478473325,"score_gpt":0.2342362455122664,"score_spread":0.2241587976649339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}