{"id":"W3127803327","doi":"10.1039/d0sc06868c","title":"Lewis acid mediated, mild C–H aminoalkylation of azoles <i>via</i> three component coupling","year":2021,"lang":"en","type":"article","venue":"Chemical Science","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Process Research Ortech (Canada)","funders":"","keywords":"Component (thermodynamics); Lewis acids and bases; Coupling (piping); Chemistry; Group (periodic table); Frustrated Lewis pair; Metal; Stereochemistry; Medicinal chemistry; Organic chemistry; Materials science; Catalysis; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002269544,0.00057398,0.0002190584,0.0001996149,0.0002075213,0.0002294728,0.0004745724,0.0004197406,0.001874132],"category_scores_gemma":[0.0002175384,0.000194859,0.0002429586,0.0002114498,0.0002528411,0.0004178569,0.000340325,0.0007561222,0.0007689031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003368664,"about_ca_system_score_gemma":0.0003446724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006825507,"about_ca_topic_score_gemma":0.002069686,"domain_scores_codex":[0.9998266,0.00002091623,0.00001108405,0.00003527795,0.000035862,0.00007024018],"domain_scores_gemma":[0.9999342,0.00001095162,0.0000191707,0.00001001319,0.00001200808,0.00001356553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007987089,0.00003148943,0.00005170217,0.0001248311,0.00001285383,0.0001278319,0.00004901476,0.0002897048,0.9920046,0.001276096,0.0004359467,0.005516112],"study_design_scores_gemma":[0.000008886293,0.0001945343,0.0002325337,0.00000411555,0.000005789494,0.00007819128,0.000008491481,0.0004652806,0.9959189,0.00008818993,0.002984262,0.00001069294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9175355,0.002407095,0.05003962,0.0004499132,0.0002450174,0.0002127287,0.0007450274,0.000729382,0.02763563],"genre_scores_gemma":[0.9824343,0.001558279,0.009761136,0.0001471048,0.00003425834,0.00006777002,0.0003260219,0.00005411141,0.005616923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001874132,"threshold_uncertainty_score":0.006269574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03151376136266686,"score_gpt":0.2820135635836593,"score_spread":0.2504998022209924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}