{"id":"W3128114328","doi":"10.3389/fphys.2021.624165","title":"Regulation of a Trehalose-Specific Facilitated Transporter (TRET) by Insulin and Adipokinetic Hormone in Rhodnius prolixus, a Vector of Chagas Disease","year":2021,"lang":"en","type":"article","venue":"Frontiers in Physiology","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Adipokinetic hormone; Trehalose; Rhodnius prolixus; Hemolymph; Vitellogenesis; Biology; Trehalase; Hormone; Cell biology; Endocrinology; Lipid metabolism; Internal medicine; Carbohydrate metabolism; Biochemistry; Insect; Neuropeptide; Receptor; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001145737,0.0002962244,0.0002360788,0.0001985131,0.0001097582,0.0002806213,0.0001632695,0.0002166099,0.0005423692],"category_scores_gemma":[0.00009928661,0.0001490097,0.0002810773,0.00008940892,0.000238371,0.0001813012,0.0002096537,0.0004622071,0.000198736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003493408,"about_ca_system_score_gemma":0.0001329452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001258315,"about_ca_topic_score_gemma":0.001779841,"domain_scores_codex":[0.9998906,0.00001586945,0.00001178625,0.00003746837,0.00002015607,0.00002411004],"domain_scores_gemma":[0.9998803,0.0000184131,0.00004592061,0.00001125525,0.000009652702,0.00003447909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000633725,0.000007311244,0.0001192605,0.00001173446,0.000001716916,0.0000178577,0.000007501189,0.00001405766,0.9994828,0.00001981756,0.000006121632,0.0002485479],"study_design_scores_gemma":[0.00003817335,0.0006715845,0.02015916,0.000006310589,0.00003630887,0.0002562819,0.00007888587,0.001751866,0.9752613,0.00003874706,0.001687866,0.00001356818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965649,0.0007577721,0.001482839,0.00008257157,0.00001720103,0.00002528048,0.0003502589,0.00004477652,0.0006743683],"genre_scores_gemma":[0.9918476,0.0006920405,0.002916279,0.00006757126,0.000008314074,0.0000478619,0.0008423362,0.00003678827,0.003541264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001258315,"threshold_uncertainty_score":0.002534688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01516693723780146,"score_gpt":0.2353888163576999,"score_spread":0.2202218791198984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}