{"id":"W3128190649","doi":"10.4049/jimmunol.2001009","title":"IgG Epitopes Processed and Presented by IgG+ B Cells Induce Suppression by Human Thymic-Derived Regulatory T Cells","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; Praespero; Ministry of Science and Technology, Taiwan; Georgia Clinical and Translational Science Alliance; American Heart Association","keywords":"Immunology; Epitope; Immune system; Proinflammatory cytokine; Rheumatoid arthritis; T cell; Biology; Myeloid; Antibody; Phenotype; Gene; Inflammation; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000200036,0.000354258,0.0002374066,0.0001685007,0.00009123315,0.0002315873,0.0001035094,0.000231041,0.001303754],"category_scores_gemma":[0.0002343643,0.0001477949,0.0001775288,0.00008483701,0.0001714034,0.00006057585,0.0001232382,0.0004991531,0.0004639624],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001136576,"about_ca_system_score_gemma":0.0001570228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003471884,"about_ca_topic_score_gemma":0.0003419353,"domain_scores_codex":[0.9998062,0.00004998894,0.00001268003,0.0000268504,0.00003355408,0.00007072715],"domain_scores_gemma":[0.9998893,0.00003620474,0.0000177926,0.00001637044,0.000009966431,0.00003034398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006177063,0.0001700001,0.0004150308,0.00004328217,0.000004881798,0.0001346564,0.00002657264,0.00007557794,0.9954516,0.00003101206,0.0000619186,0.002967863],"study_design_scores_gemma":[0.0006372569,0.008156512,0.02415494,0.00003429751,0.00007449596,0.001477899,0.000110573,0.001896395,0.9595175,0.0001850386,0.003742884,0.00001224574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980078,0.0005907904,0.0002960879,0.00002123329,0.00002517508,0.00002037632,0.00003956216,0.00003443445,0.0009644558],"genre_scores_gemma":[0.998485,0.000379256,0.0002455559,0.00005443069,0.00003395291,0.00001674357,0.0001087411,0.000007633831,0.0006686855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001303754,"threshold_uncertainty_score":0.00436151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008587988718831596,"score_gpt":0.2217868552680772,"score_spread":0.2131988665492456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}