{"id":"W3128227568","doi":"10.1242/dev.194167","title":"Golgi localization of the LIN-2/7/10 complex points to a role in basolateral secretion of LET-23 EGFR in the <i>Caenorhabditis elegans</i> vulval precursor cells","year":2021,"lang":"en","type":"article","venue":"Development","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Biology; Caenorhabditis elegans; Golgi apparatus; Cell biology; Colocalization; Cytoplasm; Epithelial polarity; Endosome; Secretion; Membrane protein; Cell; Biochemistry; Membrane; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007552699,0.0003441379,0.0001601842,0.0002620961,0.0003286385,0.0004416874,0.0003417695,0.0003760542,0.001362673],"category_scores_gemma":[0.00006324398,0.0002657226,0.0003082023,0.0000670159,0.0002855547,0.0002209756,0.0004154548,0.0007812097,0.0009048117],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001054821,"about_ca_system_score_gemma":0.0004674294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00331597,"about_ca_topic_score_gemma":0.006391933,"domain_scores_codex":[0.9998901,0.000009038694,0.000007622602,0.00002703014,0.00003700577,0.00002929666],"domain_scores_gemma":[0.9998877,0.000008016301,0.00002440267,0.00001193078,0.00001725142,0.00005066497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001680271,0.000005720189,0.0001541459,0.000008685831,0.000002116073,0.00005255846,0.000006127645,0.0000276545,0.9993668,0.0001057704,0.00002694118,0.0002267117],"study_design_scores_gemma":[0.0000106344,0.00005721634,0.01301909,0.00001120537,0.00001208424,0.0004987546,0.00007283921,0.001675827,0.9812159,0.00009134447,0.003327419,0.000007756945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912878,0.0006361628,0.004172283,0.0001477579,0.00003880517,0.00002221118,0.0003675185,0.0001828911,0.003144703],"genre_scores_gemma":[0.9888565,0.0002531288,0.003594721,0.00007769398,0.000004161398,0.00002374921,0.0006060345,0.00007383328,0.006510166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00331597,"threshold_uncertainty_score":0.007653296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008721418037897806,"score_gpt":0.214949953870348,"score_spread":0.2062285358324502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}