{"id":"W3128229494","doi":"10.1186/s13063-021-05081-3","title":"A quadruple blinded placebo controlled randomised trial to evaluate the effectiveness of an Iodine complex for patients with mild to moderate COVID-19 in Pakistan (I-COVID-PK): A structured summary of a study protocol for a randomised controlled trial","year":2021,"lang":"en","type":"letter","venue":"Trials","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Medicine; Placebo; Radiological weapon; Randomized controlled trial; Coronavirus disease 2019 (COVID-19); Iodine; Clinical trial; Internal medicine; Surgery; Disease; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","metaepi_broad"],"consensus_categories":["metaresearch","metaepi_narrow"],"category_scores_codex":[0.08344848,0.001453585,0.0216095,0.001205689,0.000342403,0.0001560048,0.0009810075,0.0008212989,0.000158937],"category_scores_gemma":[0.5090217,0.0007874854,0.003189511,0.001059923,0.0003515835,0.00008676301,0.0002788402,0.001171917,7.922668e-7],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001049898,"about_ca_system_score_gemma":0.009386022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006017123,"about_ca_topic_score_gemma":0.000533395,"domain_scores_codex":[0.9460548,0.03854087,0.008599993,0.00214347,0.003338904,0.00132203],"domain_scores_gemma":[0.6350627,0.3556254,0.003263288,0.001858163,0.003407603,0.0007828582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9639763,0.006215618,0.00002969711,0.006135698,0.008887568,0.00005214202,0.001039676,0.001414493,0.0005785073,0.000004104585,0.01152928,0.0001369555],"study_design_scores_gemma":[0.9234737,0.06325404,0.00005160606,0.0009509482,0.005404881,2.890668e-7,0.0001376346,0.001319371,0.0001513299,0.0003062954,0.00426808,0.0006818066],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.06182753,0.00001289381,0.003006575,0.02514168,0.0003766383,0.9079565,0.001607591,0.00006019443,0.0000103549],"genre_scores_gemma":[0.03686045,0.000001746584,0.0005472647,0.03168378,0.001754116,0.9281908,0.0006500009,0.000185889,0.0001260007],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.4255732,"threshold_uncertainty_score":0.9998214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2236548167730012,"score_gpt":0.5404614145625075,"score_spread":0.3168065977895063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}