{"id":"W3128453949","doi":"10.1177/1093526620986502","title":"Bilateral Nephroblastic Tumors and a Complex Renal Vascular Anomaly in a Patient With a Mosaic RASopathy: Novel Histopathologic Features and Molecular Insights","year":2021,"lang":"en","type":"article","venue":"Pediatric and Developmental Pathology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"KRAS; Wilms' tumor; Vascular anomaly; Pathology; Germline mutation; Phenotype; Cancer research; Somatic cell; Biology; Medicine; Mutation; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006349203,0.0002353583,0.0002632641,0.0001100721,0.0000919829,0.00002467952,0.00005077401,0.0001809482,0.000003994638],"category_scores_gemma":[0.00002761736,0.000182774,0.00002958433,0.0001867986,0.0001790744,0.00000831408,0.0001902645,0.000158257,8.560847e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002663963,"about_ca_system_score_gemma":0.000151471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001839925,"about_ca_topic_score_gemma":0.00004790338,"domain_scores_codex":[0.9987332,0.00007314645,0.0002335133,0.0005838799,0.0001042712,0.0002719878],"domain_scores_gemma":[0.9996559,0.00001435098,0.00007348009,0.00009897618,0.00004026288,0.0001170463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004812446,0.0002477103,0.1115806,0.0001667934,0.00009281185,0.009266317,0.001831597,0.000164598,0.8725967,0.0001500334,0.0003016784,0.003119833],"study_design_scores_gemma":[0.008444695,0.002350001,0.9130614,0.0001022332,0.0002323239,0.04311143,0.001135633,0.0001485844,0.02553366,0.0004535857,0.003759364,0.001667038],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887186,0.01048,0.0003418406,0.00006402811,0.00004354639,0.0001554069,0.00001002108,0.000009737097,0.0001767777],"genre_scores_gemma":[0.9932115,0.00180106,0.004162868,0.0005826092,0.00003585723,0.00003046647,0.0001107599,0.00001719542,0.0000476755],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8470631,"threshold_uncertainty_score":0.7453308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004544912516670468,"score_gpt":0.1816645680011505,"score_spread":0.1771196554844801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}