{"id":"W3128462096","doi":"10.3389/fimmu.2020.574569","title":"Monogenic Immune Diseases Provide Insights Into the Mechanisms and Treatment of Chronic Graft-Versus-Host Disease","year":2021,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Immunology; Immune system; Medicine; Disease; Inflammation; Graft-versus-host disease; Hematopoietic stem cell transplantation; Immunity; Transplantation; Immune dysregulation; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006434427,0.0005180543,0.0006831732,0.001060174,0.0001570405,0.0006954568,0.0004752317,0.000671866,0.002451232],"category_scores_gemma":[0.0005275221,0.0001194836,0.0003236311,0.000712426,0.0003654315,0.0008842499,0.0005266457,0.001831563,0.001182602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002749374,"about_ca_system_score_gemma":0.0005423948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002861322,"about_ca_topic_score_gemma":0.0005832638,"domain_scores_codex":[0.9997771,0.00004908623,0.00003259076,0.00003314316,0.00008535283,0.00002277082],"domain_scores_gemma":[0.9997579,0.00009238773,0.00003527518,0.00001095889,0.00007295018,0.00003046822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002331423,0.0001441141,0.0004790092,0.01157125,0.0001320891,0.0003425955,0.0000995027,0.0002681806,0.009456426,0.008205079,0.02209382,0.9469748],"study_design_scores_gemma":[0.00005570085,0.0005080322,0.002794825,0.003538684,0.0001964713,0.002146667,0.00007843715,0.000164739,0.002807672,0.005108978,0.9825736,0.0000262329],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004681311,0.9968461,0.0003915468,0.00059448,0.0003488178,0.000005839521,0.00002757286,0.000008361355,0.001309155],"genre_scores_gemma":[0.003285864,0.9943036,0.0005500929,0.0005207135,0.0005006499,0.00001246006,0.00006405322,0.000002486644,0.0007601863],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002451232,"threshold_uncertainty_score":0.008200228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01920947741528529,"score_gpt":0.2813026800369681,"score_spread":0.2620932026216828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}