{"id":"W3128502844","doi":"10.1038/s41467-021-21197-1","title":"L1 retrotransposons exploit RNA m6A modification as an evolutionary driving force","year":2021,"lang":"en","type":"article","venue":"Nature Communications","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"Institute for Basic Science; National Research Foundation of Korea; Dankook University; Compute Canada","keywords":"Retrotransposon; Exploit; RNA; Computational biology; Biology; Evolutionary biology; Computer science; Genetics; Gene; Transposable element; Genome; Computer security","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001731734,0.0002285843,0.0001149448,0.0002241762,0.0002966458,0.000432502,0.0001804129,0.0003802474,0.0008622302],"category_scores_gemma":[0.0001348676,0.00009469783,0.000186289,0.0001427519,0.0003117601,0.0002598421,0.0002669778,0.0003461412,0.0004390205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002845049,"about_ca_system_score_gemma":0.0001286528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002518177,"about_ca_topic_score_gemma":0.0004205847,"domain_scores_codex":[0.9999305,0.00001268164,0.000003381682,0.00002004866,0.00001477035,0.00001864763],"domain_scores_gemma":[0.9998701,0.00001799619,0.00005405191,0.00001653951,0.00001439291,0.00002694482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006507692,0.00001069855,0.005620244,0.00002868448,0.000006915503,0.000187173,0.0000355806,0.0001903723,0.9885342,0.0007370624,0.00004102808,0.004542989],"study_design_scores_gemma":[0.00001329558,0.0006030971,0.0515375,0.0000215215,0.00003629151,0.003192937,0.000242472,0.003652425,0.9280064,0.001005938,0.01166182,0.00002633456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934662,0.0006725966,0.003210447,0.0001291741,0.00001097883,0.00001034118,0.0000741286,0.00007493827,0.002351157],"genre_scores_gemma":[0.996425,0.0002094277,0.002112886,0.00004959386,0.000005988792,0.000003199742,0.00007868947,0.000008496015,0.001106824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008622302,"threshold_uncertainty_score":0.002884507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02390071201440219,"score_gpt":0.3172595937448202,"score_spread":0.293358881730418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}