{"id":"W3128535705","doi":"10.1111/febs.15748","title":"Inferring translational heterogeneity from <i>Saccharomyces cerevisiae</i> ribosome profiling","year":2021,"lang":"en","type":"article","venue":"FEBS Journal","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Ribosome profiling; Translation (biology); Computational biology; Saccharomyces cerevisiae; Ribosome; Biology; Eukaryotic translation; Protein biosynthesis; Translational regulation; Genetics; Messenger RNA; Gene; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000476806,0.0003451864,0.0004850118,0.0007280068,0.0002913451,0.0007736879,0.0002093976,0.0003338486,0.0004109036],"category_scores_gemma":[0.001400085,0.0001755975,0.0003432,0.0008802501,0.0002294489,0.0002668259,0.0003312152,0.0005560568,0.0003637985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000352021,"about_ca_system_score_gemma":0.0003041432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002113806,"about_ca_topic_score_gemma":0.004386414,"domain_scores_codex":[0.9997067,0.00003259797,0.00002707379,0.0001315142,0.00006896222,0.00003306273],"domain_scores_gemma":[0.9992164,0.0002649606,0.0002125851,0.0001374799,0.0001179161,0.00005051077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003622994,0.00003262832,0.04247837,0.0003227958,0.0001904944,0.000216106,0.0001071158,0.004437159,0.9356738,0.0006595817,0.0008787137,0.01464104],"study_design_scores_gemma":[0.00002937181,0.0002141835,0.2907533,0.00009903651,0.0004121141,0.0009935546,0.0003765532,0.08116325,0.6038137,0.004735267,0.01727184,0.0001378431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9513569,0.001853667,0.0360811,0.0001057189,0.0000500828,0.00002688815,0.008234119,0.0007400816,0.001551353],"genre_scores_gemma":[0.9660622,0.0007589627,0.02153594,0.0002423818,0.00002689276,0.00002935334,0.01074477,0.0002809847,0.0003183819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002113806,"threshold_uncertainty_score":0.004203022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01956458546785835,"score_gpt":0.2598491727383163,"score_spread":0.2402845872704579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}