{"id":"W3128620818","doi":"10.1007/s12325-020-01583-9","title":"Efficacy of Agomelatine 25–50 mg for the Treatment of Anxious Symptoms and Functional Impairment in Generalized Anxiety Disorder: A Meta-Analysis of Three Placebo-Controlled Studies","year":2021,"lang":"en","type":"review","venue":"Advances in Therapy","topic":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","field":"Psychology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Servier","keywords":"Agomelatine; Placebo; Medicine; Internal medicine; Anxiety; Randomized controlled trial; Generalized anxiety disorder; Meta-analysis; Placebo-controlled study; Psychiatry; Antidepressant; Double blind","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01235549,0.002603471,0.01624659,0.00396518,0.0005970562,0.003032807,0.001624991,0.001902616,0.002771564],"category_scores_gemma":[0.01452882,0.001412491,0.03799074,0.003453133,0.0007704139,0.001111467,0.0008891413,0.001521721,0.000205296],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001753282,"about_ca_system_score_gemma":0.00150079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002558439,"about_ca_topic_score_gemma":0.005404767,"domain_scores_codex":[0.9941649,0.003047362,0.001360627,0.0007081269,0.0005589428,0.0001600821],"domain_scores_gemma":[0.9925209,0.004704743,0.001772941,0.0003451729,0.0004787144,0.0001774845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.03053868,0.000155904,0.002667086,0.1133828,0.8329335,0.00009954248,0.00007283545,0.0006710351,0.00109893,0.00008314619,0.0003314769,0.01796509],"study_design_scores_gemma":[0.007563339,0.001365623,0.004413415,0.004618478,0.980459,0.0000804579,0.00002875484,0.0002023238,0.0002378995,0.0001361406,0.0008696752,0.00002495571],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03425215,0.9626364,0.0009211347,0.0002681904,0.0002793267,0.0005702099,0.0005163981,0.00006928334,0.0004868891],"genre_scores_gemma":[0.523972,0.4675089,0.003697054,0.001234857,0.0004268713,0.001473705,0.001144812,0.00007015766,0.0004717845],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01624659,"threshold_uncertainty_score":0.06534284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1321563846039023,"score_gpt":0.439351069680078,"score_spread":0.3071946850761757,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}