{"id":"W3128665491","doi":"10.1093/ndt/gfab022","title":"Voclosporin: a novel calcineurin inhibitor with no impact on mycophenolic acid levels in patients with SLE","year":2021,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Aurinia (Canada)","funders":"","keywords":"Medicine; Cmax; Mycophenolic acid; Morning; Pharmacokinetics; Tolerability; Pharmacology; Dosing; Evening; Mycophenolate; Urology; Internal medicine; Adverse effect; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007230069,0.0002995264,0.001140369,0.0001866592,0.0002289609,0.0003918934,0.0002570052,0.0005186729,0.0009098549],"category_scores_gemma":[0.000730871,0.000149391,0.0003483506,0.0002310009,0.0004140952,0.0003229026,0.0001922633,0.0007650083,0.0001996533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003356441,"about_ca_system_score_gemma":0.000547777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003138471,"about_ca_topic_score_gemma":0.0006713899,"domain_scores_codex":[0.9995992,0.0001734535,0.00003681024,0.00007531781,0.00006700246,0.00004828603],"domain_scores_gemma":[0.99951,0.0001286541,0.0001384401,0.00002683262,0.00003249424,0.0001635362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.3463878,0.01221492,0.08747013,0.001927641,0.001325149,0.001836966,0.0007424961,0.001919887,0.2338852,0.0002365513,0.00140525,0.310648],"study_design_scores_gemma":[0.07863715,0.6442353,0.2344915,0.0001357577,0.001193114,0.004970235,0.0002634473,0.002747735,0.02440693,0.0001860918,0.008671298,0.00006141281],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960889,0.003227324,0.000148266,0.00008877207,0.00001633378,0.00005959114,0.00008340319,0.00001527698,0.0002721419],"genre_scores_gemma":[0.9982221,0.0008568316,0.0003612828,0.0001099829,0.00005082567,0.00006141017,0.00014717,0.000002519106,0.000187849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001140369,"threshold_uncertainty_score":0.003823638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01238995307562881,"score_gpt":0.2615162701050175,"score_spread":0.2491263170293887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}