{"id":"W3128831572","doi":"10.1007/s12325-021-01627-8","title":"Cost-Effectiveness Analysis of Encorafenib, Binimetinib, and Cetuximab in BRAF V600E-Mutated Metastatic Colorectal Cancer in the USA","year":2021,"lang":"en","type":"article","venue":"Advances in Therapy","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"SKiN Health","funders":"Natural Science Foundation of Hunan Province","keywords":"Cetuximab; Medicine; Internal medicine; Oncology; Colorectal cancer; Irinotecan; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002692694,0.0006885126,0.001765207,0.001478357,0.0001744232,0.001267957,0.000593823,0.0008227155,0.001912527],"category_scores_gemma":[0.007162659,0.0004288807,0.005853275,0.002118886,0.0003428181,0.0008555329,0.0005999348,0.001344647,0.00008408644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006741601,"about_ca_system_score_gemma":0.003029365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03685774,"about_ca_topic_score_gemma":0.04911236,"domain_scores_codex":[0.996989,0.001974481,0.0002118437,0.0001717589,0.0003178435,0.0003352127],"domain_scores_gemma":[0.9971913,0.001599225,0.000571363,0.00005793185,0.0002036201,0.0003767083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.3162431,0.003803092,0.2224888,0.009963009,0.08928727,0.001061667,0.0002019457,0.1629673,0.002736842,0.005268649,0.01448818,0.1714902],"study_design_scores_gemma":[0.05880345,0.04264648,0.6018316,0.002683278,0.1221861,0.001498531,0.001219986,0.1487658,0.002326567,0.003292114,0.01441757,0.0003285226],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9519145,0.03553937,0.0007353951,0.00265463,0.000232063,0.0003452023,0.005022177,0.00003477931,0.003521711],"genre_scores_gemma":[0.9926602,0.004461959,0.0003735575,0.0005862908,0.00007325324,0.0001065133,0.001331536,0.000005797669,0.0004009592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03685774,"threshold_uncertainty_score":0.07328635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04293897035453263,"score_gpt":0.3990481494591079,"score_spread":0.3561091791045752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}