{"id":"W3128947316","doi":"10.26443/mjm.v4i1.673","title":"HER2/neu Oncogene and Sensitivity to the DNA-Interactive Drug Doxorubicin","year":2020,"lang":"en","type":"article","venue":"McGill Journal of Medicine","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"McGill University","keywords":"Doxorubicin; Oncogene; Cell culture; IC50; Sulforhodamine B; Molecular biology; Cancer research; Cell; Medicine; Drug resistance; Cancer; In vitro; Chemistry; Biology; Internal medicine; Cytotoxicity; Cell cycle; Chemotherapy; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001915279,0.0001380299,0.0001581313,0.0004059072,0.00007562154,0.000239163,0.00007003781,0.000187348,0.001295369],"category_scores_gemma":[0.0004756128,0.0001751849,0.0001198518,0.0002387201,0.0001197647,0.0001505078,0.000144661,0.0002528573,0.0001933164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002197614,"about_ca_system_score_gemma":0.0001121631,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008554852,"about_ca_topic_score_gemma":0.001131501,"domain_scores_codex":[0.9998423,0.00003443217,0.00002170036,0.00003083173,0.0000446494,0.00002604918],"domain_scores_gemma":[0.9996626,0.0001011023,0.0001107632,0.00002971509,0.00004558758,0.00005018619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004439029,0.00008866059,0.06840049,0.00003975275,0.00004920541,0.0001906799,0.00006432013,0.0002119283,0.9271981,0.00004974775,0.00009351591,0.003169729],"study_design_scores_gemma":[0.00001322226,0.0009180023,0.6512662,0.000006947168,0.00005113094,0.001760494,0.0001294202,0.001391293,0.3431796,0.00004847271,0.001224879,0.00001042132],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987765,0.0005880354,0.0001370877,0.0000179505,0.000002730668,0.000005055664,0.0001047829,0.000007324335,0.0003604891],"genre_scores_gemma":[0.9990168,0.0001976231,0.0001211904,0.00001672955,0.0000020437,0.000005821233,0.0002013421,0.000001347053,0.000437216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001295369,"threshold_uncertainty_score":0.004333377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06253521179347514,"score_gpt":0.3734550808636167,"score_spread":0.3109198690701416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}