{"id":"W3128973213","doi":"10.3390/cancers13030560","title":"89Zr-Labeled Domain II-Specific scFv-Fc ImmunoPET Probe for Imaging Epidermal Growth Factor Receptor In Vivo","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal University Hospital; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Saskatchewan Health Research Foundation","keywords":"In vivo; Nimotuzumab; Chemistry; Epidermal growth factor receptor; Biodistribution; In vitro; Antibody; Epitope; Monoclonal antibody; Molecular biology; Cancer research; Epitope mapping; Receptor; Biology; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000202156,0.0003644577,0.0003341553,0.0001787268,0.00009056148,0.0002284006,0.0004329211,0.0005563023,0.0009291499],"category_scores_gemma":[0.0001083874,0.000197139,0.0001998941,0.0001751135,0.0001352346,0.0002388405,0.0001765903,0.0004045659,0.000419927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003350459,"about_ca_system_score_gemma":0.0001685647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005994085,"about_ca_topic_score_gemma":0.0005250425,"domain_scores_codex":[0.9998796,0.00002939906,0.000004510058,0.00003445652,0.00002377986,0.00002810545],"domain_scores_gemma":[0.9999689,0.000008073798,0.000007021913,0.00000449935,0.000005709396,0.000005777633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005449423,0.00001629089,0.00008730813,0.00003764768,0.00000431533,0.00005187122,0.000008602717,0.0001208386,0.9979932,0.0001327407,0.00008955418,0.001403101],"study_design_scores_gemma":[0.00001425519,0.0002504046,0.000788667,0.000005155389,0.00002037486,0.0005318387,0.000009136407,0.003599588,0.9919177,0.00003371249,0.002823022,0.000006133864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.889604,0.006067265,0.09736541,0.0003266222,0.00007939268,0.0001602952,0.0004659975,0.000409825,0.005521127],"genre_scores_gemma":[0.9393145,0.002663361,0.05040567,0.0002021739,0.00001994316,0.0001415699,0.0007624662,0.00008281091,0.006407528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009291499,"threshold_uncertainty_score":0.003108323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02992373257691718,"score_gpt":0.3164395211303886,"score_spread":0.2865157885534715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}