{"id":"W3128973213","doi":"10.3390/cancers13030560","title":"89Zr-Labeled Domain II-Specific scFv-Fc ImmunoPET Probe for Imaging Epidermal Growth Factor Receptor In Vivo","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal University Hospital; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Saskatchewan Health Research Foundation","keywords":"In vivo; Nimotuzumab; Chemistry; Epidermal growth factor receptor; Biodistribution; In vitro; Antibody; Epitope; Monoclonal antibody; Molecular biology; Cancer research; Epitope mapping; Receptor; Biology; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001075839,0.0001559289,0.0002753633,0.00006567738,0.00013361,0.00002054318,0.0001036063,0.00006303519,0.0010387],"category_scores_gemma":[0.00008324,0.0001558802,0.00009602124,0.0005589778,0.0001006378,0.00008017886,0.00003464513,0.0002386488,0.00001644815],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007824075,"about_ca_system_score_gemma":0.000443628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001770735,"about_ca_topic_score_gemma":0.000004309147,"domain_scores_codex":[0.9988195,0.0000215877,0.0002923167,0.0003768059,0.000130438,0.000359296],"domain_scores_gemma":[0.9993026,0.00008464308,0.00005753168,0.0002595267,0.0001256458,0.0001700767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002024035,0.00005320117,0.0006661676,0.0001674528,0.00003126435,0.00002149575,0.0002636644,0.0000077237,0.9799031,0.0008486375,0.01653562,0.001299247],"study_design_scores_gemma":[0.002202605,0.00002575213,0.0001950209,0.0001076042,0.00001897246,0.00002443089,0.0002639617,0.0001615341,0.64144,0.0001992969,0.3552039,0.0001568729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9660279,0.004837724,0.002268004,0.01617057,0.0003936477,0.001319348,0.0003553831,0.0001320675,0.008495369],"genre_scores_gemma":[0.9811445,0.0009580993,0.01111452,0.001544727,0.0006359735,0.0007620215,0.0001690696,0.00005431802,0.003616797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3386683,"threshold_uncertainty_score":0.9998745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02992373257691718,"score_gpt":0.3164395211303886,"score_spread":0.2865157885534715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}