{"id":"W3129074806","doi":"10.1371/journal.pgen.1009352","title":"Steroid hormone ecdysone deficiency stimulates preparation for photoperiodic reproductive diapause","year":2021,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Fundamental Research Funds for the Central Universities; Natural Science Foundation of Hubei Province; National Natural Science Foundation of China","keywords":"Diapause; Biology; Ecdysone; Ecdysone receptor; Vitellogenesis; Endocrinology; Internal medicine; Juvenile hormone; Steroid hormone; 20-Hydroxyecdysone; Cell biology; Hormone; Transcription factor; Botany; Nuclear receptor; Genetics; Gene; Oocyte; Embryo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118404,0.0001415327,0.0001955195,0.00005179553,0.0002892338,0.00004106391,0.0002230014,0.00009711502,0.00004937841],"category_scores_gemma":[0.001246997,0.0001329508,0.0000574875,0.0002438402,0.0002511874,0.00008928905,0.0001377328,0.0001730409,0.00007985166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001998863,"about_ca_system_score_gemma":0.0001103575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":5.464733e-7,"about_ca_topic_score_gemma":0.00000218837,"domain_scores_codex":[0.998244,0.0002422741,0.0002261213,0.0007776989,0.0001440379,0.0003658183],"domain_scores_gemma":[0.9988015,0.000353605,0.00006928267,0.0005425351,0.000170845,0.0000622497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000202723,0.0003002707,0.0002051286,0.00001958379,0.000007567516,0.000008967203,0.0003059544,0.0003575647,0.9980745,0.00008728072,0.0003362795,0.00009416483],"study_design_scores_gemma":[0.0004281373,0.00079901,0.001032719,0.000004154759,0.0000163331,0.00001914103,0.0000221379,0.003467604,0.9927347,0.0009270862,0.0004070241,0.0001418937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977204,0.0008186036,0.00008512862,0.0001994325,0.0001682623,0.000578724,0.00005274025,0.00005776401,0.0003189986],"genre_scores_gemma":[0.9980411,0.0003910845,0.0002356553,0.000403458,0.000119742,0.0001232251,0.0000217338,0.0000209061,0.0006431119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005339756,"threshold_uncertainty_score":0.5421576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06333349318621649,"score_gpt":0.3210632039714268,"score_spread":0.2577297107852103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}