{"id":"W3129348349","doi":"10.18433/jpps31455","title":"Epithelial and Endothelial Expressions of ACE2: SARS-CoV-2 Entry Routes","year":2021,"lang":"en","type":"review","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Angiotensin-converting enzyme 2; Receptor; Biology; TMPRSS2; Viral entry; Basigin; Homeostasis; Cell; Lung; Cell biology; Immunology; Virus; Internal medicine; Medicine; Matrix metalloproteinase; Biochemistry; Disease; Coronavirus disease 2019 (COVID-19); Viral replication","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002068845,0.0002455136,0.0002725535,0.0003722674,0.0003658674,0.0009112926,0.0001645724,0.0004565513,0.004686647],"category_scores_gemma":[0.0001795732,0.0001639277,0.0004319719,0.0003934402,0.0001538532,0.0006405413,0.0002736583,0.0009425931,0.001259732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005232755,"about_ca_system_score_gemma":0.0003868287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001403677,"about_ca_topic_score_gemma":0.0009978518,"domain_scores_codex":[0.9997558,0.00002794331,0.00001724222,0.00004932681,0.00006721349,0.00008237454],"domain_scores_gemma":[0.9998393,0.00001300022,0.00002787514,0.00001158403,0.00007111842,0.00003703065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001247937,0.0002476886,0.005702372,0.0006782624,0.0000612304,0.001475629,0.0002479368,0.0001652875,0.9678661,0.002998167,0.001374909,0.01793439],"study_design_scores_gemma":[0.0001678511,0.001593851,0.1061377,0.0001937751,0.0002674088,0.01189067,0.001289445,0.005369652,0.7953364,0.001815247,0.07587258,0.00006548232],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9176449,0.03767211,0.01285817,0.001117301,0.0004855185,0.0001851545,0.002753918,0.0002555273,0.02702749],"genre_scores_gemma":[0.9593681,0.01136899,0.004785807,0.0004311329,0.0002118544,0.0001023117,0.002548778,0.00003229079,0.02115081],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.004686647,"threshold_uncertainty_score":0.01567841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3190516019271768,"score_gpt":0.5915270319160908,"score_spread":0.272475429988914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}