{"id":"W3129686488","doi":"10.1055/s-0040-1706023","title":"Recent Advances in Transition-Metal-Free (4+3)-Annulations","year":2021,"lang":"en","type":"article","venue":"Synthesis","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"Synthon; Chemistry; Lewis acids and bases; Catalysis; Cycloisomerization; Pyrrole; Acid catalysis; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001929429,0.0001112704,0.0001761165,0.00007293927,0.00006733827,0.00002293246,0.0001282055,0.00007937784,0.02396745],"category_scores_gemma":[0.002391146,0.0001258592,0.00008639319,0.0004455751,0.00003829281,0.0001895225,0.00003290554,0.0000934271,0.00005686385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001063979,"about_ca_system_score_gemma":0.0001123047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007150701,"about_ca_topic_score_gemma":0.0001344431,"domain_scores_codex":[0.9989761,0.00005680394,0.0002828557,0.0002872074,0.0002386771,0.0001583597],"domain_scores_gemma":[0.9985753,0.0007030642,0.00005479732,0.0004838344,0.0001280267,0.00005493579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001139653,0.0009386526,0.004955601,0.0004690831,0.000184909,0.0001370961,0.001112118,0.01152776,0.1341618,0.0115363,0.004128556,0.8307342],"study_design_scores_gemma":[0.0005044219,0.000002988346,0.001500044,0.0001415561,0.00009416314,0.00004315017,0.000813165,0.001145913,0.3142215,0.009754231,0.6714224,0.0003564688],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.1093424,0.04750693,0.08498575,0.03004618,0.001635198,0.0003745163,0.001202541,0.0008417354,0.7240647],"genre_scores_gemma":[0.7817118,0.04333952,0.1271764,0.002683815,0.002288034,0.001194824,0.001918041,0.0004161193,0.03927143],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8303778,"threshold_uncertainty_score":0.9769248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02079624996070065,"score_gpt":0.2856896460936852,"score_spread":0.2648933961329846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}