{"id":"W3129780093","doi":"10.1016/s0140-6736(21)00152-5","title":"A comparison of sunitinib with cabozantinib, crizotinib, and savolitinib for treatment of advanced papillary renal cell carcinoma: a randomised, open-label, phase 2 trial","year":2021,"lang":"en","type":"article","venue":"The Lancet","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":279,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Health Science Centre","funders":"National Cancer Institute; National Institutes of Health; Wayne State University","keywords":"Cabozantinib; Sunitinib; Medicine; Crizotinib; Renal cell carcinoma; Oncology; Internal medicine; Papillary renal cell carcinomas; Urology; Carcinoma; Foolishness; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003083393,0.0003027496,0.001991413,0.0000547685,0.0001026475,0.00002663045,0.0001865651,0.00007268872,0.00005094538],"category_scores_gemma":[0.0001048991,0.0001778613,0.0001263866,0.0001899528,0.0002063286,0.00005818721,0.00007328448,0.00008686222,0.000001084875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005149707,"about_ca_system_score_gemma":0.0003944834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007839991,"about_ca_topic_score_gemma":0.00003448592,"domain_scores_codex":[0.9980574,0.0002103164,0.0006725864,0.0003970067,0.0002794514,0.0003832637],"domain_scores_gemma":[0.9975803,0.000750354,0.0004500251,0.0007806784,0.0002938536,0.000144798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8709374,0.008623194,0.004604403,0.0007724501,0.0005090925,0.0002005953,0.002607037,0.000009882599,0.09984498,0.0002992436,0.001197953,0.01039377],"study_design_scores_gemma":[0.625618,0.01892694,0.001077371,0.0001323944,0.0008706454,0.00007632585,0.0009167232,0.00008037825,0.3483704,0.00003168403,0.00375817,0.0001410044],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858589,0.00469819,0.0000396396,0.0007035608,0.00007807369,0.004203699,0.000320787,0.00001858604,0.004078614],"genre_scores_gemma":[0.9931263,0.0002698453,0.004767213,0.00009259724,0.0003425008,0.0004415894,0.000257428,0.0000415233,0.0006610182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2485254,"threshold_uncertainty_score":0.7252975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1253189226571554,"score_gpt":0.3859075263052156,"score_spread":0.2605886036480602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}