{"id":"W3130050547","doi":"","title":"Upregulation of STAT1 transcription activator by an androgen agonist in prostate cancer cells affects intracellular cholesterol esterification","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"LNCaP; Sterol O-acyltransferase; Endocrinology; Internal medicine; Androgen; Androgen receptor; Cholesteryl ester; Chemistry; Agonist; Cholesterol; Prostate cancer; Biology; Medicine; Receptor; Cancer; Lipoprotein; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007412408,0.0002742224,0.0002441094,0.0002007718,0.0001578775,0.0003046037,0.0001046223,0.0001310044,0.002418645],"category_scores_gemma":[0.00005982782,0.0001071599,0.000324208,0.00023486,0.0001562649,0.0001146881,0.0001218819,0.0004146182,0.0007064945],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00028376,"about_ca_system_score_gemma":0.0002993637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001012678,"about_ca_topic_score_gemma":0.002141668,"domain_scores_codex":[0.9998837,0.00001651969,0.00001112134,0.00001936306,0.00003848998,0.00003083762],"domain_scores_gemma":[0.9999563,0.000009816008,0.000009920811,0.000005775511,0.000006361077,0.00001196457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002087905,0.00004153274,0.0003175445,0.00005983208,0.000004044244,0.0000476746,0.00001798859,0.00006280228,0.99773,0.00004581962,0.00006519751,0.001398967],"study_design_scores_gemma":[0.00002087154,0.00075055,0.00957175,0.000007468211,0.00001992307,0.0002144174,0.00008034791,0.0006619273,0.9841532,0.00002787213,0.004486456,0.000005262516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886231,0.005956444,0.001179447,0.0001669333,0.00008245496,0.00002428975,0.001271494,0.0001095759,0.002586186],"genre_scores_gemma":[0.9890252,0.002515606,0.0009099628,0.00008371042,0.00001903491,0.00003391894,0.002226341,0.00001693706,0.005169376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002418645,"threshold_uncertainty_score":0.008091152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02669325549996378,"score_gpt":0.3462429509296385,"score_spread":0.3195496954296748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}