{"id":"W3130053491","doi":"10.1042/ns20200095","title":"The life cycle of voltage-gated Ca2+ channels in neurons: an update on the trafficking of neuronal calcium channels","year":2021,"lang":"en","type":"review","venue":"Neuronal Signaling","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Endoplasmic reticulum; Cell biology; Neuroscience; Endocytosis; Calcium signaling; Biology; Voltage-dependent calcium channel; Sodium channel; Stretch-activated ion channel; Neurotransmission; Ion channel; Intracellular; Voltage-gated ion channel; Chemistry; Calcium; Cell; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005017283,0.000883739,0.001140835,0.00192712,0.0002972321,0.001087108,0.0007803306,0.00104928,0.002323724],"category_scores_gemma":[0.0006824587,0.00023421,0.0003951114,0.002878872,0.00047234,0.001966892,0.000709965,0.00187453,0.001599866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006717384,"about_ca_system_score_gemma":0.001087549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007371244,"about_ca_topic_score_gemma":0.001148992,"domain_scores_codex":[0.9998621,0.00002308034,0.00002143541,0.00002558883,0.00005278267,0.00001493191],"domain_scores_gemma":[0.9996566,0.0001648403,0.00003810357,0.00001036141,0.00009588494,0.00003411887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001021889,0.00006965905,0.0002003562,0.02106069,0.0000905206,0.0003590768,0.0001463933,0.000530677,0.004061937,0.008355724,0.08625079,0.878772],"study_design_scores_gemma":[0.000007388041,0.00005998584,0.0004056738,0.002739622,0.00007969929,0.0008450567,0.00005431107,0.00006980207,0.0003425482,0.002219049,0.993162,0.00001479487],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009252226,0.998381,0.0001490899,0.0003484519,0.0004469063,0.00000167349,0.00001540928,0.000006996636,0.0005578694],"genre_scores_gemma":[0.000432448,0.9984173,0.0001629401,0.0002095203,0.0003293185,0.000003128734,0.00002514969,0.000001696472,0.0004185548],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002323724,"threshold_uncertainty_score":0.007773578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05432469673597287,"score_gpt":0.3062518501467113,"score_spread":0.2519271534107385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}