{"id":"W3130205045","doi":"10.1007/s00281-021-00846-z","title":"Recent advances on the role of cytotoxic T lymphocytes in the pathogenesis of spondyloarthritis","year":2021,"lang":"en","type":"review","venue":"Seminars in Immunopathology","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Toronto Western Hospital; University Health Network","funders":"Arthritis Society","keywords":"Pathogenesis; CTL*; Immunology; Immune system; Cytotoxic T cell; Inflammation; Biology; Immune dysregulation; Phenotype; Medicine; CD8; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008185454,0.0004100131,0.002456842,0.0003057019,0.00006222914,0.000005587276,0.0003773086,0.0002969124,0.0001041593],"category_scores_gemma":[0.0005335418,0.00024545,0.0004271682,0.0009418147,0.0003848946,0.00002527794,0.0001561961,0.0003992124,0.00001347996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001896817,"about_ca_system_score_gemma":0.0002764138,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001788462,"about_ca_topic_score_gemma":0.00005584409,"domain_scores_codex":[0.9968523,0.0009287918,0.001065217,0.0004567281,0.0003065548,0.0003904437],"domain_scores_gemma":[0.997288,0.00115023,0.0005132026,0.0009386852,0.000087386,0.00002253629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009054237,0.0005228931,0.0009809673,0.0009274684,0.0000747849,0.001427668,0.0005851159,3.33895e-7,0.00009029084,0.0002344242,0.00001448085,0.995051],"study_design_scores_gemma":[0.001425179,0.001240728,0.001864615,0.0428999,0.0004450844,0.002381395,0.003024394,2.236767e-7,0.0002531528,0.0001540027,0.9460737,0.00023761],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03230689,0.9648668,5.211955e-8,0.00007122547,0.0002432582,0.00115521,0.000130551,0.000006404838,0.001219638],"genre_scores_gemma":[0.003663285,0.9953957,0.00005919153,0.00006979927,0.00003841603,0.0005752276,0.000117193,0.00004149257,0.00003975982],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9948134,"threshold_uncertainty_score":0.9999998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02105244374724661,"score_gpt":0.3064335948133166,"score_spread":0.28538115106607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}