{"id":"W3130231895","doi":"10.1007/s11060-020-03584-8","title":"Clinical significance of checkpoint regulator “Programmed death ligand-1 (PD-L1)” expression in meningioma: review of the current status","year":2021,"lang":"en","type":"review","venue":"Journal of Neuro-Oncology","topic":"Meningioma and schwannoma management","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Immune checkpoint; Clinical trial; Tumor microenvironment; Oncology; Meningioma; Immunotherapy; Internal medicine; Pathological; Refractory (planetary science); Glioma; Brain tumor; Radiation therapy; Cancer research; Cancer; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001120678,0.0005763625,0.001100038,0.002256555,0.0002363973,0.001041131,0.0007669239,0.000966542,0.001317258],"category_scores_gemma":[0.001857639,0.0002539004,0.0007673132,0.001980464,0.0004472481,0.001271904,0.0004828518,0.001124964,0.0004631481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00081299,"about_ca_system_score_gemma":0.001166864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001134929,"about_ca_topic_score_gemma":0.001436647,"domain_scores_codex":[0.9996681,0.00007421819,0.00008898594,0.00006793169,0.00007741938,0.00002329376],"domain_scores_gemma":[0.9988128,0.0006420132,0.0001800283,0.00002042177,0.0002955455,0.00004927708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002467069,0.00006040985,0.001765804,0.04148905,0.0002928318,0.000422711,0.0001626324,0.0004333097,0.001631564,0.002351589,0.03936713,0.9117763],"study_design_scores_gemma":[0.0000471781,0.0004474896,0.008573294,0.02964674,0.001403033,0.00651255,0.0003788279,0.0005238383,0.00185925,0.003048952,0.9474725,0.0000863686],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002061081,0.9987607,0.00008309038,0.000453646,0.0001810245,0.00000331073,0.00002103344,0.000003977289,0.0002870521],"genre_scores_gemma":[0.002249427,0.9964037,0.0002137773,0.0003931858,0.0005098315,0.000008710911,0.00004894426,0.000001975842,0.0001704851],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002256555,"threshold_uncertainty_score":0.005926728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1314382919086039,"score_gpt":0.449951934765504,"score_spread":0.3185136428569001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}