{"id":"W3130243787","doi":"10.3390/curroncol28010088","title":"Very Delayed Acute Hepatitis after Pembrolizumab Therapy for Advanced Malignancy: How Long Should We Watch?","year":2021,"lang":"en","type":"article","venue":"Current Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Pembrolizumab; Malignancy; Natural history; Adverse effect; Hepatitis; Immune system; Hepatitis C; Immunology; Internal medicine; Immunotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005403754,0.0002676392,0.0005649191,0.0003616586,0.0006711879,0.0008483006,0.0002763191,0.001480361,0.0009251803],"category_scores_gemma":[0.00168877,0.0001335669,0.0003888984,0.0002366371,0.0005315563,0.001254258,0.0004032239,0.002168972,0.0002885523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004543099,"about_ca_system_score_gemma":0.0004029277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007736761,"about_ca_topic_score_gemma":0.001465813,"domain_scores_codex":[0.9997148,0.00008087864,0.00003102227,0.00004580538,0.00005440991,0.00007300201],"domain_scores_gemma":[0.9992498,0.0002607015,0.0002023059,0.00003524055,0.00006229478,0.0001897462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.001302686,0.0003204759,0.1679849,0.0006262264,0.0001833249,0.6293058,0.0008592947,0.0005461681,0.008886497,0.002223677,0.008378213,0.1793827],"study_design_scores_gemma":[0.0001489432,0.0009308445,0.09861567,0.001309474,0.0001861649,0.8568845,0.001180061,0.001432909,0.0029264,0.004090734,0.03220497,0.00008932554],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7860048,0.1398999,0.01138413,0.03837414,0.002062733,0.0002476548,0.0001684106,0.0002784611,0.02157973],"genre_scores_gemma":[0.9723618,0.01508535,0.001276598,0.007541934,0.002009796,0.000018246,0.0001205391,0.00002604015,0.001559663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001480361,"threshold_uncertainty_score":0.003296256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07249969318809091,"score_gpt":0.3856125077407154,"score_spread":0.3131128145526245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}