{"id":"W3130256579","doi":"10.1158/1538-7445.sabcs20-sp87","title":"Abstract SP087: Epigenetic therapy against high-risk breast cancer","year":2021,"lang":"en","type":"article","venue":"Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Breast cancer; Epigenetics; Oncology; Internal medicine; Cancer; Disease; Adjuvant therapy; Chemotherapy; Epigenetic therapy; Hormonal therapy; Bioinformatics; DNA methylation; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004083013,0.0005034198,0.0003208031,0.0004853691,0.0004259755,0.001089888,0.0005478298,0.0009953452,0.04033252],"category_scores_gemma":[0.0002878642,0.0001076295,0.0002757554,0.0002429026,0.0002587094,0.0004906483,0.0006405083,0.001366414,0.008087026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007107622,"about_ca_system_score_gemma":0.0006618062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009534605,"about_ca_topic_score_gemma":0.002892591,"domain_scores_codex":[0.9998817,0.00002689425,0.000005408149,0.00001885499,0.00004379981,0.00002337028],"domain_scores_gemma":[0.9998947,0.00001544445,0.000009987095,0.000005993071,0.00003108377,0.00004270902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001384701,0.0003412688,0.0004014525,0.0007164334,0.00003376226,0.0004023308,0.00007602777,0.0004374546,0.03180576,0.004923268,0.5852956,0.374182],"study_design_scores_gemma":[0.0003953664,0.001152292,0.002712927,0.0003814736,0.00006465873,0.0007364964,0.00009532566,0.0008067063,0.02328501,0.002183978,0.9681576,0.00002824474],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.06095571,0.2754753,0.01246064,0.07782292,0.06749586,0.001334345,0.008699389,0.003737688,0.4920181],"genre_scores_gemma":[0.1661408,0.1452397,0.009789968,0.02858787,0.009994184,0.0006157781,0.00758551,0.0005593212,0.6314869],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.04033252,"threshold_uncertainty_score":0.1349257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04586144509366474,"score_gpt":0.3801195846881927,"score_spread":0.3342581395945279,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}