{"id":"W3130296909","doi":"10.1016/j.cell.2021.01.049","title":"Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis","year":2021,"lang":"en","type":"article","venue":"Cell","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":258,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"National Human Genome Research Institute; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health; National Science Foundation","keywords":"Biology; Haematopoiesis; Stem cell; Hematopoietic stem cell; Somatic cell; Immunology; Cell division; Cell biology; Cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004016028,0.0003853683,0.0003226511,0.0008008975,0.0001998731,0.0004751119,0.0001992735,0.0004204031,0.00304114],"category_scores_gemma":[0.0003161016,0.0002671833,0.0002741035,0.0002596707,0.0002304883,0.0002735435,0.0003484625,0.0009652297,0.0006031567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001937737,"about_ca_system_score_gemma":0.000252429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000274887,"about_ca_topic_score_gemma":0.0004464528,"domain_scores_codex":[0.9998075,0.00005260516,0.00001062703,0.00002260637,0.00006314828,0.0000435035],"domain_scores_gemma":[0.9997736,0.00004131568,0.00004613161,0.00003280312,0.00002717968,0.00007904078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001694798,0.0001463892,0.002932225,0.00007247821,0.00001513464,0.0003815392,0.00005020677,0.00009263174,0.9810175,0.0010151,0.0002562948,0.01232578],"study_design_scores_gemma":[0.0002003561,0.001540831,0.05581598,0.00002786176,0.00009353401,0.001303079,0.000113831,0.001548939,0.9301428,0.0008124853,0.008388317,0.00001193564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905675,0.002949552,0.002791965,0.0002471107,0.00009599231,0.00002887569,0.0001399965,0.0001625027,0.003016465],"genre_scores_gemma":[0.9907872,0.00160512,0.001875431,0.00008235028,0.0001288991,0.00003033313,0.0001914002,0.00002952874,0.005269714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00304114,"threshold_uncertainty_score":0.01017368,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03034732483575423,"score_gpt":0.2723801921477868,"score_spread":0.2420328673120326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}