{"id":"W3130296909","doi":"10.1016/j.cell.2021.01.049","title":"Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis","year":2021,"lang":"en","type":"article","venue":"Cell","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":258,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"National Human Genome Research Institute; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health; National Science Foundation","keywords":"Biology; Haematopoiesis; Stem cell; Hematopoietic stem cell; Somatic cell; Immunology; Cell division; Cell biology; Cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002831753,0.0001646703,0.000310763,0.000133023,0.00006434543,0.00006239778,0.0001107475,0.0001537801,0.0007704394],"category_scores_gemma":[0.00003803974,0.0001536112,0.00008362109,0.0005173351,0.00004309425,0.0001090458,0.00009637154,0.0003511738,0.0003286636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003382759,"about_ca_system_score_gemma":0.000690056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001153437,"about_ca_topic_score_gemma":0.00004179933,"domain_scores_codex":[0.9984534,0.0001325435,0.0003054536,0.0003738698,0.0003694675,0.0003653157],"domain_scores_gemma":[0.9990709,0.0001290345,0.00005476447,0.0003661445,0.0001988076,0.0001803813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001948844,0.00068943,0.08795702,0.0005196638,0.0000207301,0.0002250897,0.0009568495,0.00001307471,0.9015163,0.00003301074,0.007205743,0.0006682468],"study_design_scores_gemma":[0.002802915,0.00008571448,0.02907158,0.00007743909,0.00002562216,0.00002515238,0.0006021814,0.001002312,0.9646599,0.00003246358,0.001462642,0.0001520624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988072,0.0004321492,0.00005888052,0.000678317,0.00005233776,0.0003802602,0.00001024901,0.00005340152,0.01026234],"genre_scores_gemma":[0.9878039,0.0001447317,0.001005222,0.0006395193,0.0001323693,0.00007231485,0.00009499952,0.00003994073,0.01006699],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06314366,"threshold_uncertainty_score":0.8435771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03034732483575423,"score_gpt":0.2723801921477868,"score_spread":0.2420328673120326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}