{"id":"W3130492453","doi":"10.1016/j.transproceed.2021.01.034","title":"Renal Function and Patient-Reported Outcomes in Stable Kidney Transplant Patients Following Conversion From Twice-Daily Immediate-Release Tacrolimus to Once-Daily Prolonged-Release Tacrolimus: A 12-Month Observational Study in Routine Clinical Practice in Germany (ADAGIO)","year":2021,"lang":"en","type":"article","venue":"Transplantation Proceedings","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bayer Vital; Novartis Pharma; Bristol-Myers Squibb Canada; Pfizer; Vifor Pharma; Bristol-Myers Squibb; AstraZeneca; Chiesi Farmaceutici; Sanofi; Amgen; Astellas Pharma; Ablynx; Alexion Pharmaceuticals; Roche","keywords":"Tacrolimus; Medicine; Observational study; Renal function; Kidney transplantation; Kidney transplant; Kidney; Calcineurin; Urology; Transplantation; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006603206,0.0005268891,0.001000375,0.0005159174,0.0001233906,0.00009742993,0.0001136491,0.0002699399,0.00004772625],"category_scores_gemma":[0.0004847919,0.0004961702,0.0001922383,0.0008663907,0.00004285495,0.001210052,0.00002243677,0.0006390103,0.00001634941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00025171,"about_ca_system_score_gemma":0.0003872808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002074745,"about_ca_topic_score_gemma":0.0009851513,"domain_scores_codex":[0.9948942,0.0001950483,0.002071833,0.001130256,0.001101097,0.0006075802],"domain_scores_gemma":[0.9978655,0.0005555055,0.0004579634,0.0001977447,0.0003817638,0.0005415193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01590075,0.004412018,0.9613255,0.000292292,0.0004064006,0.002422116,0.01302082,0.00006033571,0.001364531,0.00001395558,0.00002383902,0.0007574042],"study_design_scores_gemma":[0.04373081,0.00171073,0.9487216,0.001234339,0.0009860389,0.00004860852,0.002202687,0.0003229247,0.0004807363,0.00003589761,0.000099022,0.000426566],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948244,0.00009997456,0.00008631867,0.001415896,0.0003607287,0.002650051,0.0002923111,0.00007610017,0.0001942154],"genre_scores_gemma":[0.9936214,0.000381233,0.001005134,0.003010112,0.00004639041,0.0002896862,0.001519079,0.00005912381,0.00006780959],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02783005,"threshold_uncertainty_score":0.999749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03560563777173384,"score_gpt":0.3179302114225078,"score_spread":0.2823245736507739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}